ArticleInternational journal of environmental research and public health2024
The Relationship between All-Cause Dementia and Acute Diabetes Complications among American Indian and Alaska Native Peoples.
Article in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 2 citations in OpenAlex.
- Incidence and risk factors for AD/ADRD among American Indian and Alaska Native US Veterans.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Article
- Machine learning to predict dementia for American Indian and Alaska native peoples: a retrospective cohort study.Lancet regional health. Americas · 2025Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAmerican Indian and Alaska Native people (AI/AN) bear a disproportionate burden of diabetes. Growing evidence shows significant associations between several acute diabetes complications and dementia among diabetes patients. However, little is known about these relationships among AI/AN adults. Here, we aim to investigate these associations among AI/AN adults.
methodsThis cross-sectional study extracted data from the Indian Health Service's (IHS) National Data Warehouse and related administrative databases. A total of 29,337 IHS actual users with diabetes who were 45+ years old during fiscal year 2013 were included. All-cause dementia and diabetes complications were identified using ICD-9 diagnostic codes. Negative binomial regression models were used to evaluate the associations of interest.
resultsNearly 3% of AI/AN diabetes patients had a dementia diagnosis. After controlling for covariates, dementia was associated with a 94% higher rate of severe
conclusionsAI/AN diabetes patients with dementia suffered from considerably higher rates of acute diabetes complications than their counterparts without dementia. The clinical management of patients with comorbid diabetes and dementia is particularly challenging and may require individualized treatment approaches.
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