Evidence map›Paper›PMID 38673407›Full record

ArticleInternational journal of environmental research and public health2024

The Relationship between All-Cause Dementia and Acute Diabetes Complications among American Indian and Alaska Native Peoples.

Xiaoyi Niu, Jenny Chang, Maria M Corrada, Ann Bullock, Blythe Winchester, Spero M Manson, Joan O'Connell, Luohua Jiang

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Incidence and risk factors for AD/ADRD among American Indian and Alaska Native US Veterans.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xiaoyi NiuDepartment of Epidemiology & Biostatistics, University of California Irvine, Irvine, CA 92697, USA.
Jenny ChangDepartment of Medicine, University of California Irvine, Irvine, CA 92697, USA.
Maria M CorradaDepartment of Epidemiology & Biostatistics, University of California Irvine, Irvine, CA 92697, USA.ORCID 0000-0002-8168-8593
Ann BullockFormerly with the Division of Diabetes Treatment and Prevention, Indian Health Service, Rockville, MD 20857, USA.
Blythe WinchesterCherokee Indian Hospital, Cherokee, NC 28719, USA.
Spero M MansonCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Joan O'ConnellCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Luohua JiangDepartment of Epidemiology & Biostatistics, University of California Irvine, Irvine, CA 92697, USA.
University of California, Irvine · USColorado School of Public Health · USIndian Health Service · USMuseum of the Cherokee Indian · US

Funding

TRANSLATIONAL RESEARCH COREP30DK092923 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Angela Gwen Brega · 2011 to 2026
$10.2M
Longitudinal Study of MRI, Clinical, and Genetic Biomarkers of Cognitive Impairment and Alzheimer's Disease in Elderly American IndiansU54MD000507 · NIMHD · UNIVERSITY OF COLORADO DENVER · PI MANSON, SPERO MARTIN · 2017 to 2021
$6.5M
Dementia epidemiology, health service utilization and treatment costs among American Indian and Alaska Native EldersR01AG061189 · NIA · UNIVERSITY OF COLORADO DENVER · PI JIANG, LUOHUA, OCONNELL, JOAN M · 2019 to 2023
$2.9M
Effectiveness of advanced practice pharmacy services among American Indian and Alaska Native adults with diabetesR18DK114757 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MANSON, SPERO MARTIN, OCONNELL, JOAN M · 2017 to 2019
$681k
NIA NIH HHS R01 AG061189NIA NIH HHS R01AG061189NIDDK NIH HHS P30 DK092923NIDDK NIH HHS P30DK092923NIDDK NIH HHS R18DK114757NIMHD NIH HHS U54 MD000507
6 · The paper itself

Abstract

backgroundAmerican Indian and Alaska Native people (AI/AN) bear a disproportionate burden of diabetes. Growing evidence shows significant associations between several acute diabetes complications and dementia among diabetes patients. However, little is known about these relationships among AI/AN adults. Here, we aim to investigate these associations among AI/AN adults.

methodsThis cross-sectional study extracted data from the Indian Health Service's (IHS) National Data Warehouse and related administrative databases. A total of 29,337 IHS actual users with diabetes who were 45+ years old during fiscal year 2013 were included. All-cause dementia and diabetes complications were identified using ICD-9 diagnostic codes. Negative binomial regression models were used to evaluate the associations of interest.

resultsNearly 3% of AI/AN diabetes patients had a dementia diagnosis. After controlling for covariates, dementia was associated with a 94% higher rate of severe

conclusionsAI/AN diabetes patients with dementia suffered from considerably higher rates of acute diabetes complications than their counterparts without dementia. The clinical management of patients with comorbid diabetes and dementia is particularly challenging and may require individualized treatment approaches.

Indexed as

Alaska NativesDementiaDiabetes ComplicationsIndians, North AmericanAgedAged, 80 and overAmerican Indian or Alaska NativeCross-Sectional StudiesFemaleHumansMaleMiddle AgedUnited StatesAlzheimer’s diseaseAmerican Indian or Alaska Nativedementiadiabetic ketoacidosishyperglycemiahypoglycemia

Identifiers

PMID38673407
PMCPMC11049920
OpenAlexW4394919022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.