Evidence map›Paper›PMID 38672996›Full record

ArticleJournal of personalized medicine2024

Oropharyngeal Microbiome Analysis in Patients with Varying SARS-CoV-2 Infection Severity: A Prospective Cohort Study.

Panagiotis Siasios, Evangelia Giosi, Konstantinos Ouranos, Maria Christoforidi, Ifigenia Dimopoulou, Enada Leshi, Maria Exindari, Cleo Anastassopoulou, Georgia Gioula

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Panagiotis SiasiosMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-8094-9317
Evangelia GiosiMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Konstantinos OuranosDepartment of Medicine, Houston Methodist Research Institute, Houston, TX 77030, USA.ORCID 0000-0001-9034-5026
Maria ChristoforidiMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Ifigenia DimopoulouMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Enada LeshiMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Maria ExindariMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-4052-8550
Cleo AnastassopoulouDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-7666-9198
Georgia GioulaMicrobiology Department, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRHouston Methodist · USNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with COVID-19 infection have distinct oropharyngeal microbiota composition and diversity metrics according to disease severity. However, these findings are not consistent across the literature. We conducted a multicenter, prospective study in patients with COVID-19 requiring outpatient versus inpatient management to explore the microbial abundance of taxa at the phylum, family, genus, and species level, and we utilized alpha and beta diversity indices to further describe our findings. We collected oropharyngeal washing specimens at the time of study entry, which coincided with the COVID-19 diagnosis, to conduct all analyses. We included 43 patients in the study, of whom 16 were managed as outpatients and 27 required hospitalization.

Indexed as

bacterial abundancebacterial diversityoropharyngeal microbiomeSARS-CoV-2 infection

Identifiers

PMID38672996
PMCPMC11051038
OpenAlexW4393356998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.