Evidence map›Paper›PMID 38672972›Full record

ReviewJournal of personalized medicine2024

The Impact of Periodontal Disease on Preterm Birth and Preeclampsia.

Panagiotis Tsikouras, Efthymios Oikonomou, Konstantinos Nikolettos, Sotiris Andreou, Dimitrios Kyriakou, Christos Damaskos, Nikolaos Garmpis, Vassiliki Monastiridou, Theopi Nalmpanti, Anastasia Bothou and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Panagiotis TsikourasDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Efthymios OikonomouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0009-0005-2177-953X
Konstantinos NikolettosDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Sotiris AndreouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Dimitrios KyriakouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Christos DamaskosDepartment of Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-5454-2564
Nikolaos GarmpisDepartment of Surgery, Sotiria Hospital, 11527 Athens, Greece.ORCID 0000-0001-9980-0056
Vassiliki MonastiridouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Theopi NalmpantiDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Anastasia BothouNeonatal Department, University Hospital Alexandra, 11528 Athens, Greece.
George IatrakisDepartment of Obstetrics and Gynecology, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-8958-1248
Nikolaos NikolettosDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Democritus University of Thrace · GRNational and Kapodistrian University of Athens · GRSotiria General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review delves into the possible connection between periodontitis and negative pregnancy outcomes, such as preeclampsia and preterm birth. It highlights the potential influence of an unidentified microbial factor on preeclampsia and the effects of inflammatory responses on the rate of preterm births. Furthermore, it underscores the prevalent occurrence of oral ailments within the populace and their significant repercussions on quality of life. Hormonal fluctuations during pregnancy may exacerbate oral conditions such as pregnancy gingivitis and periodontitis, necessitating bespoke therapeutic approaches that take into account potential fetal ramifications. Periodontal disease, characterized by microbial attack and inflammatory response, results in tissue destruction and tooth loss. The oral cavity's susceptibility to bacterial colonization, which is primarily due to its role as a site for food intake, is highlighted. Furthermore, research indicates a correlation between inflammatory responses and factors such as prostaglandin E2 and IL-1β, and preterm birth. Therapeutic interventions are a focus of international research, with efforts being aimed at optimizing outcomes through larger studies involving pregnant women.

Indexed as

adverse effectperiodontal diseasepregnancy outcome

Identifiers

PMID38672972
PMCPMC11051368
OpenAlexW4393188805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.