Evidence map›Paper›PMID 38672942›Full record

ArticleFoods (Basel, Switzerland)2024

Dietary Factors and Risk of Gout: A Two-Sample Mendelian Randomization Study.

Guosen Ou, Jialin Wu, Shiqi Wang, Yawen Jiang, Yaokang Chen, Jingwen Kong, Huachong Xu, Li Deng, Huan Zhao, Xiaoyin Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Guosen OuSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-6218-9596
Jialin WuSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Shiqi WangSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-2379-0426
Yawen JiangSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Yaokang ChenSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Jingwen KongSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Huachong XuSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-4046-7599
Li DengSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-1522-4184
Huan ZhaoSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Xiaoyin ChenSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-1519-4501
Lu XuSchool of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.ORCID 0009-0004-7198-3072
Jinan University · CN

Funding

China Postdoctoral Science Foundation 2021M701443Fundamental Research Funds for the Central Universities 21621003Guangdong Basic and Applied Basic Research Foundation 2022A1515110827National Natural Science Foundation of China 82374016Scientific research project of Guangdong Provincial Bureau of Traditional Chinese Medicine 20241065
6 · The paper itself

Abstract

backgroundDietary intervention is the preferred approach for the prevention and clinical management of gout. Nevertheless, the existing evidence regarding the influence of specific foods on gout is insufficient.

methodsWe used two-sample Mendelian randomization for genetic prediction to analyze the relationship between the intake of more than a dozen daily food items, such as pork, beef, cheese, and poultry, and dietary macronutrient intake (fat, protein, carbohydrates, and sugar) and the risk of developing gout and elevating the serum uric acid level. Inverse-variance weighted MR analyses were used as the main evaluation method, and the reliability of the results was tested by a sensitivity analysis.

resultsCheese intake was associated with lower serum uric acid levels, and tea intake (OR = 0.523, [95%CI: 0.348~0.784],

conclusionsThese results will significantly contribute to the formulation and refinement of nutritional strategies tailored to patients afflicted with gout.

Indexed as

foodgoutmacronutrientmendelian randomization analysisuric acid

Identifiers

PMID38672942
PMCPMC11049247
OpenAlexW4395010177

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.