Evidence map›Paper›PMID 38672751›Full record

ArticleLife (Basel, Switzerland)2024

Early Intervention Guided by the General Movements Examination at Term Corrected Age-Short Term Outcomes.

Adrian Ioan Toma, Vlad Dima, Adelina Alexe, Cristina Bojan, Alexandra Floriana Nemeș, Bogdan Florin Gonț, Alexandra Arghirescu, Andreea Ioana Necula, Alina Fieraru, Roxana Stoiciu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
8.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Adrian Ioan TomaLife Memorial Hospital, 010719 Bucharest, Romania.
Vlad DimaNeonatology Department Filantropia Clinical Hospital, 011132 Bucharest, Romania.ORCID 0000-0001-5969-9205
Adelina AlexeIndependent Researcher, 10067 Ploiesti, Romania.
Cristina BojanKinetotherapy Department, Pediatric Neurology Alexandru Obregia Hospital, 041914 Bucharest, Romania.
Alexandra Floriana NemeșLife Memorial Hospital, 010719 Bucharest, Romania.
Bogdan Florin GonțLife Memorial Hospital, 010719 Bucharest, Romania.
Alexandra ArghirescuLife Memorial Hospital, 010719 Bucharest, Romania.
Andreea Ioana NeculaLife Memorial Hospital, 010719 Bucharest, Romania.
Alina FieraruLife Memorial Hospital, 010719 Bucharest, Romania.
Roxana StoiciuLife Memorial Hospital, 010719 Bucharest, Romania.
Andrada MireaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Andreea Calomfirescu AvramescuNeonatology Department Filantropia Clinical Hospital, 011132 Bucharest, Romania.
Al Jashi IsamFaculty of Medicine, University Titu Maiorescu, 040441 Bucharest, Romania.
Clinical Emergency Hospital Bucharest · ROTitu Maiorescu University · ROCarol Davila University of Medicine and Pharmacy · ROPetroleum & Gas University of Ploieşti · ROSpitalul Clinic de Psihiatrie Alexandru Obregia · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe early identification of the former premature neonates at risk of neurologic sequelae could lead to early intervention and a better prognosis. This pilot study aimed to investigate whether the General Movement patterns observed at term-equivalent age in former premature infants could serve as predictors for guiding early intervention and improving prognosis. MATERIALS AND

methodsIn a population of 44 premature neonates (mean gestational age 33.59 weeks (+2.43 weeks)) examined at term-equivalent age, 10 neonates with a cramped-synchronized General Movements motor pattern were identified. These neonates were included in an early intervention program consisting of physiotherapy executed both by the therapist and by the parents at home. They were again examined at a corrected age of 12 weeks. The presence or absence of fidgety movements and the MOS-R (motor optimality score revised) was noted. The examinations were performed by certified specialists.

resultsNormal fidgety movements and a MOS-R of 20-24 were presented in 9/10 of the former premature infants, with normal foot to foot contact present in 7/10, and normal hand to hand contact present in 5/10. The atypical patterns noted were side to side movements of the head in 5/10, a non-centered head in 9/10, asymmetric tonic neck reflex in 9/10 and jerky movements in 10/10. One patient presented with no fidgety movements and a MOS-R score of 9.

conclusionEarly intervention in our group of patients allowed for an improvement in the neurologic status, demonstrated by the presence of fidgety movements. We suggest that early intervention should be indicated in all premature infants that present with a cramped-synchronized GM pattern during examination at term-equivalent age. However, due to the small sample size, the absence of statistical analysis and a control group, and the limited follow-up period, the conclusions must be approached with caution.

Indexed as

cramped–synchronizedearly interventionfidgetygeneral movements

Identifiers

PMID38672751
PMCPMC11050901
OpenAlexW4394580420

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.