Evidence map›Paper›PMID 38672696›Full record

ArticleLife (Basel, Switzerland)2024

Low Left-Ventricular Ejection Fraction as a Predictor of Intraprocedural Cardiopulmonary Resuscitation in Patients Undergoing Transcatheter Aortic Valve Implantation.

Stephen Gerfer, Clara Großmann, Hannah Gablac, Ahmed Elderia, Hendrik Wienemann, Ihor Krasivskyi, Navid Mader, Samuel Lee, Victor Mauri, Ilija Djordjevic and 5 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Stephen GerferDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0002-6568-6766
Clara GroßmannDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0001-8747-496X
Hannah GablacDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Ahmed ElderiaDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0002-6859-5384
Hendrik WienemannClinic for Cardiology, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0001-5810-2868
Ihor KrasivskyiDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0003-0573-8218
Navid MaderDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Samuel LeeClinic for Cardiology, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Victor MauriClinic for Cardiology, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Ilija DjordjevicDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0002-5810-8626
Matti AdamClinic for Cardiology, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Elmar KuhnDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Stephan BaldusClinic for Cardiology, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Kaveh EghbalzadehDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.
Thorsten WahlersDepartment of Cardiothoracic Surgery, Heart Center of the University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany.ORCID 0000-0002-8437-4119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcatheter aortic valve replacement (TAVR) has become an established alternative to surgical aortic valve replacement (AVR) for patients with moderate-to-high perioperative risk. Periprocedural TAVR complications decrease with growing expertise of implanters. Nevertheless, TAVR can still be accompanied by life-threatening adverse events such as intraprocedural cardiopulmonary resuscitation (CPR). This study analyzed the role of a reduced left-ventricular ejection fraction (LVEF) in intraprocedural complications during TAVR. Perioperative and postoperative outcomes from patients undergoing TAVR in a high-volume center (600 cases per year) were analyzed retrospectively with regard to their left-ventricular ejection fraction. Patients with a reduced left-ventricular ejection fraction (EF ≤ 40%) faced a significantly higher risk of perioperative adverse events. Within this cohort, patients were significantly more often in need of mechanical ventilation (35% vs. 19%). These patients also underwent CPR (17% vs. 5.8%), defibrillation due to ventricular fibrillation (13% vs. 5.4%), and heart-lung circulatory support (6.1% vs. 2.5%) more often. However, these intraprocedural adverse events showed no significant impact on postoperative outcomes regarding in-hospital mortality, stroke, or in-hospital stay. A reduced preprocedural LVEF is a risk factor for intraprocedural adverse events. With respect to this finding, the identified patient cohort should be treated with more caution to prevent intraprocedural incidents.

Indexed as

intraprocedural cardiopulmonary resuscitation (CPR)reduced left-ventricular ejection fraction (LVEF)TAVR

Identifiers

PMID38672696
PMCPMC11051090

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.