Evidence map›Paper›PMID 38672689›Full record

ArticleCancers2024

Effects of Adjuvant Exercise and Nutrition Therapy on Muscle Fibre Biomechanics in Gastrointestinal Cancer Patients.

Michael Haug, Raphaela Schwappacher, Charlotte Pollmann, Paul Ritter, Mena Michael, Hans Joachim Hermann, Robert Grützmann, Anke Mittelstädt, Markus Friedrich Neurath, Yurdagül Zopf and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Michael HaugInstitute of Medical Biotechnology (MBT), Department of Chemical and Biological Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0001-5968-2593
Raphaela SchwappacherHector-Centre for Nutrition, Exercise and Sports, Medical Department 1, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.
Charlotte PollmannInstitute of Medical Biotechnology (MBT), Department of Chemical and Biological Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.
Paul RitterInstitute of Medical Biotechnology (MBT), Department of Chemical and Biological Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0001-9227-8031
Mena MichaelInstitute of Medical Biotechnology (MBT), Department of Chemical and Biological Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0003-4805-0333
Hans Joachim HermannHector-Centre for Nutrition, Exercise and Sports, Medical Department 1, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.
Robert GrützmannDepartment of General and Visceral Surgery, Friedrich-Alexander-University Erlangen-Nürnberg, Krankenhausstr. 12, 91054 Erlangen, Germany.
Anke MittelstädtDepartment of General and Visceral Surgery, Friedrich-Alexander-University Erlangen-Nürnberg, Krankenhausstr. 12, 91054 Erlangen, Germany.ORCID 0009-0009-1716-3547
Markus Friedrich NeurathMedical Department 1, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.
Yurdagül ZopfHector-Centre for Nutrition, Exercise and Sports, Medical Department 1, Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.ORCID 0000-0002-3432-7488
Oliver FriedrichInstitute of Medical Biotechnology (MBT), Department of Chemical and Biological Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0003-2238-2049
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

ELAN programme Interdisziplinäres Zentrum für klinische Forschung, IZKF, University Clinic Erlangen, GermanyEmerging Talents Initiative ETI 2021-1-Tech-05-HaugErlangen Graduate School in Advanced Optical Technologies GSC 80Friedrich-Alexander-Universität Erlangen-Nürnberg Open Access Publication FundingHector Foundation II n.a.Marohn-Stiftung Myo-DesStaedtler-Stiftung DS/eh 11/14
6 · The paper itself

Abstract

Patients with aggressive cancer, e.g., gastrointestinal cancer, are prone (≥50% chance) to developing cancer cachexia (CC). Little is known about the effects of CC on the biomechanical function of muscle. A promising prevention strategy was found in the form of a multi-modal therapy combining mild resistance exercise (e.g., whole-body electro-myostimulation, WB-EMS) and a protein-rich diet. In a previous study of ours, this was effective in counteracting the loss of muscle mass, yet a systematic and comprehensive assessment of active and passive single muscle fibre functions was so far absent. This pilot study investigated the biomechanical function of single muscle fibres (

Indexed as

cancer cachexiamulti-modal therapyprotein-rich dietresistance trainingsingle fibresskeletal muscle

Identifiers

PMID38672689
PMCPMC11049604
OpenAlexW4394999102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.