Evidence map›Paper›PMID 38672677›Full record

ArticleCancers2024

Correlation of Molecular Status with Preoperative Olfactory Function in Olfactory Groove Meningioma.

Dino Podlesek, Friederike Beyer, Majd Alkhatib, Dirk Daubner, Mido Max Hijazi, Jerry Hadi Juratli, Susanne Weise, Ilker Y Eyüpoglu, Gabriele Schackert, Tareq A Juratli and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Dino PodlesekDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0001-5518-6496
Friederike BeyerDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Majd AlkhatibDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Dirk DaubnerInstitute of Diagnostic and Interventional Neuroradiology, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Mido Max HijaziDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Jerry Hadi JuratliDepartment of Otorhinolaryngology, Smell & Taste Clinic, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0003-2167-5077
Susanne WeiseDepartment of Otorhinolaryngology, Smell & Taste Clinic, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0001-7650-1731
Ilker Y EyüpogluDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Gabriele SchackertDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Tareq A JuratliDepartment of Neurosurgery, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.
Thomas HummelDepartment of Otorhinolaryngology, Smell & Taste Clinic, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0001-9713-0183
University Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study aims to examine the possible correlation between genomic alterations and preoperative olfactory function in patients with olfactory groove meningioma (OGM), due to the frequent presence of olfactory impairment.

methodsWe utilised next-generation sequencing to analyse samples from 22 individuals with OGM in order to detect driver mutations. Tumour morphology was assessed using preoperative imaging, whereas olfactory function was examined using Sniffin' Sticks.

resultsIn a study of 22 OGM patients, mutations were as follows: 10 with

conclusionThe study highlights PSH and perifocal oedema's significant effect on olfactory function in OGM patients but finds no link between olfactory impairment and tumour mutations, possibly due to the small sample size. This suggests that age and gender affect olfactory impairment. Additional research with a larger group of participants is needed to explore the impact of OGM driver mutations on olfactory performance.

Indexed as

AKT1 and SMO mutationolfactory groove meningiomasolfactory impairmentpreoperative phenotypic characteristics of OGM

Identifiers

PMID38672677
PMCPMC11048944
OpenAlexW4395009812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.