Evidence map›Paper›PMID 38672653›Full record

ArticleCancers2024

The Genomic, Transcriptomic, and Immunologic Landscape of

Samuel A Kareff, Asaad Trabolsi, Harris B Krause, Timothy Samec, Andrew Elliott, Estelamari Rodriguez, Coral Olazagasti, Dionysios C Watson, Matias A Bustos, Dave S B Hoon and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Samuel A KareffDepartment of Graduate Medical Education, University of Miami Sylvester Comprehensive Cancer Center/Jackson Memorial Hospital, Miami, FL 33136, USA.ORCID 0000-0001-7431-1221
Asaad TrabolsiDepartment of Graduate Medical Education, University of Miami Sylvester Comprehensive Cancer Center/Jackson Memorial Hospital, Miami, FL 33136, USA.ORCID 0000-0002-2479-1797
Harris B KrauseCaris Life Sciences, Phoenix, AZ 85040, USA.ORCID 0000-0003-3481-8364
Timothy SamecCaris Life Sciences, Phoenix, AZ 85040, USA.ORCID 0000-0003-3468-7165
Andrew ElliottCaris Life Sciences, Phoenix, AZ 85040, USA.ORCID 0000-0001-8494-8031
Estelamari RodriguezDivision of Medical Oncology, Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.ORCID 0000-0001-8132-4573
Coral OlazagastiDivision of Medical Oncology, Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.
Dionysios C WatsonDivision of Medical Oncology, Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.
Matias A BustosDivision of Translational Molecular Medicine, St. Johns' Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.ORCID 0000-0001-9625-1127
Dave S B HoonDivision of Translational Molecular Medicine, St. Johns' Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.
Stephanie L GraffDepartment of Medicine, Lifespan Cancer Institute, Providence, RI 02903, USA.ORCID 0000-0003-1928-1722
Emmanuel S AntonarakisDivision of Hematology, Oncology, and Transplantation, University of Minnesota Masonic Cancer Center, Minneapolis, MN 55455, USA.ORCID 0000-0003-3531-3851
Sanjay GoelDivision of Medical Oncology, Rutgers University, New Brunswick, NJ 08901, USA.ORCID 0000-0002-2798-7568
George SledgeCaris Life Sciences, Phoenix, AZ 85040, USA.
Gilberto LopesDivision of Medical Oncology, Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.
Caris Life Sciences (United States) · USUniversity of Miami · USJackson Memorial Hospital · USSaint John's Health Center · USProvidence College · USRutgers, The State University of New Jersey · USUniversity of Minnesota · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller · 1998 to 2026
$100.4M
Mitochondrial transfer from astrocytes to glioblastoma cells drives tumor growthR00CA277242 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dionysios C Watson · 2024 to 2026
$632k
Mitochondrial transfer from astrocytes to glioblastoma cells drives tumor growthK99CA277242 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI WATSON, DIONYSIOS C · 2023 to 2024
$319k
NCI NIH HHS K99 CA277242NCI NIH HHS P30 CA077598NCI NIH HHS R00 CA277242
6 · The paper itself

Abstract

Tipifarnib is the only targeted therapy breakthrough for

Indexed as

biomarkersHRASprecision oncologytipifarnibtranslational oncology

Identifiers

PMID38672653
PMCPMC11049662
OpenAlexW4394952811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.