ReviewCancers2024
Long-Term Impact of Severe Postoperative Complications after Esophagectomy for Cancer: Individual Patient Data Meta-Analysis.
Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Does Lymph Node Dissection During Esophagectomy Impact the Long-Term Prognosis for Complete Responders After Neoadjuvant Therapy? A Meta-analysis.Annals of surgical oncology · 2026Pooled it
- Association of preoperative psoas muscle index with clinical outcomes in surgical esophageal cancer patients: a meta-analysis.BMC gastroenterology · 2026Pooled it
- Impact of Centralizing Esophageal Cancer Surgery at High-Volume Centers on Long-Term Survival: Individual Patient Data Meta-Analysis.Annals of surgical oncology · 2025Pooled it
- Effects of Postoperative Complications on Overall Survival Following Esophagectomy: A Meta-Analysis Using the Restricted Mean Survival Time Analysis.Thoracic cancer · 2025Pooled it
- Comparison of the efficacy of different treatments after non-curative endoscopic resection of superficial esophageal carcinoma: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Routine Intraoperative ICG Perfusion Assessment and Anastomotic Leak After Esophagectomy: A Before-After Cohort Study.Journal of clinical medicine · 2026Article
- Prognostic impact of recurrent laryngeal nerve palsy after esophagectomy: a systematic review and reconstructed individual patient data meta-analysis.Journal of thoracic disease · 2026Article
- The complication sum score: A Delphi-based approach to summarize treatment related complications for esophageal cancer.Clinical and translational radiation oncology · 2026Article
- Postoperative Septic Shock After Esophagectomy for Esophageal Cancer: Risk Factors and Impact on Short- and Long-Term Survival.Journal of personalized medicine · 2026Article
- Outcomes after laparoscopic transhiatal esophagectomy for siewert type I esophagogastric junction adenocarcinoma: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- Impact of Preoperative Sarcopenia on Patient Survival After Esophagectomy for Cancer: A Retrospective Cohort Study.Annals of surgical oncology · 2026Article
- Oral Environment of Esophageal Cancer Patients, the Incidence of Complications, and Long-Term Prognoses.Current oncology (Toronto, Ont.) · 2026Review
- Comparable outcomes after McKeown and Ivor-Lewis minimally invasive esophagectomy with standardized two-field lymphadenectomy: a propensity score-matched study.Frontiers in oncology · 2026Article
- Quality of life and survival of achieving textbook outcome for resectable esophageal squamous cell carcinoma.Journal of thoracic disease · 2025Article
- Perioperative nursing care strategies in esophageal cancer surgery: a mini-review.Frontiers in oncology · 2025Review
- Postoperative complications and health-related quality of life after oesophageal cancer surgery: a national, population-based cohort study.Acta oncologica (Stockholm, Sweden) · 2024Article
- Does Indocyanine Green Utilization during Esophagectomy Prevent Anastomotic Leaks? Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere postoperative complications (SPCs) may occur after curative esophagectomy for cancer and are associated with prolonged hospital stay, augmented costs, and increased in-hospital mortality. However, the effect of SPCs on survival after esophagectomy is uncertain.
aimTo assess the impact of severe postoperative complications (SPCs) on long-term survival following curative esophagectomy for cancer, we conducted a systematic search of PubMed, MEDLINE, Scopus, and Web of Science databases up to December 2023. The included studies examined the relationship between SPCs and survival outcomes, defining SPCs as Clavien-Dindo grade > 3. The primary outcome measure was long-term overall survival (OS). We used restricted mean survival time difference (RMSTD) and 95% confidence intervals (CIs) to calculate pooled effect sizes. Additionally, we applied the GRADE methodology to evaluate the certainty of the evidence.
resultsTen studies (2181 patients) were included. SPCs were reported in 651 (29.8%) patients. The RMSTD overall survival analysis shows that at 60-month follow-up, patients experiencing SPCs lived for 8.6 months (95% Cis -12.5, -4.7;
conclusionsThis study suggests a statistically significant detrimental effect of SPCs on OS in patients undergoing curative esophagectomy for cancer. Also, a clinical trend toward reduced CSS and DFS was perceived.
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