Evidence map›Paper›PMID 38672510›Full record

ArticleBiomolecules2024

Transgenic Overexpression of HDAC9 Promotes Adipocyte Hypertrophy, Insulin Resistance and Hepatic Steatosis in Aging Mice.

Praneet Veerapaneni, Brandee Goo, Samah Ahmadieh, Hong Shi, David S Kim, Mourad Ogbi, Stephen Cave, Ronnie Chouhaita, Nicole Cyriac, David J Fulton and 6 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Praneet VeerapaneniVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0009-0000-8593-7166
Brandee GooVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0000-0002-9994-6706
Samah AhmadiehVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
Hong ShiVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
David S KimVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0000-0001-6896-6950
Mourad OgbiVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0009-0007-5887-1334
Stephen CaveVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0009-0006-4700-8458
Ronnie ChouhaitaVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
Nicole CyriacVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
David J FultonVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0000-0002-1528-1517
Alexander D VerinVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
Weiqin ChenDepartment of Physiology, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
Yun LeiDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
Xin-Yun LuDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.
Ha Won KimVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0000-0001-6272-4248
Neal L WeintraubVascular Biology Center, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, USA.ORCID 0000-0002-5138-3705
Augusta University · US

Funding

Novel Role of Bscl2 in Cardiac Substrate Metabolism and FunctionR01HL132182 · NHLBI · AUGUSTA UNIVERSITY · PI Weiqin Chen · 2016 to 2026
$4.1M
Calpain/talin/MLCP axis in pulmonary endothelial barrier regulationR01HL158909 · NHLBI · AUGUSTA UNIVERSITY · PI SU, YUNCHAO, VERIN, ALEXANDER D · 2022 to 2025
$2.9M
Neuronal HDAC9, Synaptic Plasticity and Alzheimer's DiseaseR01AG076235 · NIA · AUGUSTA UNIVERSITY · PI Xin-Yun Lu, Neal L Weintraub · 2022 to 2026
$2.8M
Epigenetic regulation of HDAC9 in obesity and atherosclerosisR01HL126949 · NHLBI · AUGUSTA UNIVERSITY · PI WEINTRAUB, NEAL L · 2016 to 2019
$1.8M
HDAC9 nuclear/cytoplasmic shuttling in pulmonary vascular endothelial barrier regulationR01HL157440 · NHLBI · AUGUSTA UNIVERSITY · PI VERIN, ALEXANDER D · 2022 to 2025
$1.5M
Novel Posttranslational Modifications in Adipose BiologyR01DK135657 · NIDDK · AUGUSTA UNIVERSITY · PI Weiqin Chen · 2024 to 2026
$1.3M
Role of Histone Deacetylase 9 (HDAC9) in adipose tissue aging: mitochondrial function, oxidative stress and senescenceF30AG074640 · NIA · AUGUSTA UNIVERSITY · PI GOO, BRANDEE · 2022 to 2024
$158k
NHLBI NIH HHS R01 HL126949NHLBI NIH HHS R01 HL132182NHLBI NIH HHS R01 HL157440NHLBI NIH HHS R01 HL158909NIA NIH HHS F30 AG074640NIA NIH HHS R01 AG076235NIDDK NIH HHS R01 DK135657NIH HHS AG076235NIH HHS HL136949
6 · The paper itself

Abstract

Histone deacetylase (HDAC) 9 is a negative regulator of adipogenic differentiation, which is required for maintenance of healthy adipose tissues. We reported that

Indexed as

AdipocytesFatty LiverHistone DeacetylasesInsulin ResistanceAgingAnimalsHypertrophyMiceMice, TransgenicRepressor ProteinsHdac9 protein, mouseHistone DeacetylasesRepressor Proteinsadipose tissueHDAC9insulin resistanceliveroverexpression

Identifiers

PMID38672510
PMCPMC11048560
OpenAlexW4394913247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.