Evidence map›Paper›PMID 38672508›Full record

ArticleBiomolecules2024

Development of Improved Spectrophotometric Assays for Biocatalytic Silyl Ether Hydrolysis.

Yuqing Lu, Chisom S Egedeuzu, Peter G Taylor, Lu Shin Wong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yuqing LuManchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK.ORCID 0000-0001-5201-0225
Chisom S EgedeuzuManchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK.ORCID 0000-0002-1380-234X
Peter G TaylorSchool of Life Health and Chemical Sciences, Open University, Milton Keynes MK7 6AA, UK.ORCID 0000-0003-3169-4466
Lu Shin WongManchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK.ORCID 0000-0002-7437-123X
University of Manchester · GBThe Open University · GB

Funding

UK Engineering and Physical Sciences Research Council EP/S013539/1, EP/K011685/1
6 · The paper itself

Abstract

Reported herein is the development of assays for the spectrophotometric quantification of biocatalytic silicon-oxygen bond hydrolysis. Central to these assays are a series of chromogenic substrates that release highly absorbing phenoxy anions upon cleavage of the sessile bond. These substrates were tested with silicatein, an enzyme from a marine sponge that is known to catalyse the hydrolysis and condensation of silyl ethers. It was found that, of the substrates tested,

Indexed as

BiocatalysisEthersSilanesSpectrophotometryAnimalsCathepsinsHydrolysisKineticsCathepsinsEthersSilanescolorimetric assayenzymehydrolaseorganosiloxanesilicatein

Identifiers

PMID38672508
PMCPMC11048244
OpenAlexW4394933073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.