Evidence map›Paper›PMID 38672471›Full record

ReviewBiomolecules2024

Atrial Fibrillation and Dementia: Pathophysiological Mechanisms and Clinical Implications.

Dimitrios Varrias, Tinatin Saralidze, Pawel Borkowski, Sumant Pargaonkar, Michail Spanos, George Bazoukis, Damianos Kokkinidis

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. NovelBiomedicines · 2026
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  13. Identification and Functional Investigation ofDiagnostics (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dimitrios VarriasDepartment of Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Tinatin SaralidzeDepartment of Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Pawel BorkowskiDepartment of Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0001-9233-6545
Sumant PargaonkarDepartment of Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-2568-2664
Michail SpanosCardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-1205-4201
George BazoukisSchool of Medicine, European University Cyprus, 2417 Nicosia, Cyprus.
Damianos KokkinidisSection of Cardiovascular Medicine, Yale University, New Haven, CT 06520, USA.
Jacobi Medical Center · USEuropean University Cyprus · CYHarvard University · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous longitudinal studies suggest a strong association between cardiovascular risk factors and cognitive impairment. Individuals with atrial fibrillation are at higher risk of dementia and cognitive dysfunction, as atrial fibrillation increases the risk of cerebral hypoperfusion, inflammation, and stroke. The lack of comprehensive understanding of the observed association and the complex relationship between these two diseases makes it very hard to provide robust guidelines on therapeutic indications. With this review, we attempt to shed some light on how atrial fibrillation is related to dementia, what we know regarding preventive interventions, and how we could move forward in managing those very frequently overlapping conditions.

Indexed as

Atrial FibrillationDementiaCognitive DysfunctionHumansRisk FactorsStrokeAlzheimer’santicoagulationatrial fibrillationbleedingdementiastroke

Identifiers

PMID38672471
PMCPMC11048426
OpenAlexW4394580887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.