Evidence map›Paper›PMID 38672468›Full record

ArticleBiomolecules2024

So Shiho Tang Reduces Inflammation in Lipopolysaccharide-Induced RAW 264.7 Macrophages and Dextran Sodium Sulfate-Induced Colitis Mice.

Mei Tong He, Geonha Park, Do Hwi Park, Minsik Choi, Sejin Ku, Seung Hyeon Go, Yun Gyo Lee, Seok Jun Song, Chang-Wook Ahn, Young Pyo Jang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Mei Tong HeCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.
Geonha ParkDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0002-7072-2602
Do Hwi ParkCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.
Minsik ChoiDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Sejin KuDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Seung Hyeon GoDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Yun Gyo LeeDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Seok Jun SongDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Chang-Wook AhnDr. Ahn's Surgery Clinic, Osan 18144, Republic of Korea.
Young Pyo JangDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0001-5865-9228
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.
Kyung Hee University · KRGachon University · KROsan University · KR

Funding

Ministry of Food and Drug Safety in 2023 21173MFDS561)
6 · The paper itself

Abstract

So Shiho Tang (SSHT) is a traditional herbal medicine commonly used in Asian countries. This study evaluated the anti-inflammatory effect of SSHT and the associated mechanism using lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages and murine dextran sodium sulfate (DSS)-induced ulcerative colitis models. Pre-treatment of RAW 264.7 macrophages with SSHT significantly reduced LPS-induced inflammation by decreasing nitrite production and regulating the mitogen-activated protein kinase pathway. Meanwhile, in mice, DSS-induced colitis symptoms, including colon shortening and body weight loss, were attenuated by SSHT. Moreover, representative compounds of SSHT, including glycyrrhizic acid, ginsenoside Rb

Indexed as

Anti-Inflammatory AgentsDextran SulfateLipopolysaccharidesMacrophagesAnimalsColitisDrugs, Chinese HerbalGinsenosidesInflammationMaleMiceOleanolic AcidRAW 264.7 CellsAnti-Inflammatory AgentsDextran SulfateDrugs, Chinese HerbalGinsenosidesLipopolysaccharidesOleanolic Acidbaicalinginsenoside Rb1glycyrrhizic acidmacrophagessaikosaponinsSo Shiho Tangulcerative colitis

Identifiers

PMID38672468
PMCPMC11047977
OpenAlexW4394580692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.