Evidence map›Paper›PMID 38672445›Full record

ArticleBiomolecules2024

Testosterone Reduces Myelin Abnormalities in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis.

Ivan J Esperante, Maria Meyer, Carolina Banzan, Maria Sol Kruse, Analia Lima, Paulina Roig, Rachida Guennoun, Michael Schumacher, Alejandro F De Nicola, Maria Claudia Gonzalez Deniselle

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ivan J EsperanteLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.ORCID 0009-0008-0822-7361
Maria MeyerLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.
Carolina BanzanLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.
Maria Sol KruseLaboratory of Neurobiology, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.
Analia LimaLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.
Paulina RoigLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.
Rachida GuennounU1195 INSERM and University Paris Sud: "Neuroprotective, Neuroregenerative and Remyelinating Small Molecules", 94276 Kremlin-Bicêtre, France.ORCID 0000-0002-9219-7300
Michael SchumacherU1195 INSERM and University Paris Sud: "Neuroprotective, Neuroregenerative and Remyelinating Small Molecules", 94276 Kremlin-Bicêtre, France.ORCID 0000-0001-6117-5371
Alejandro F De NicolaLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.ORCID 0000-0002-3523-9148
Maria Claudia Gonzalez DeniselleLaboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, CONICET, Buenos Aires 1428, Argentina.ORCID 0000-0001-9121-0019
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversité Paris-Sud · FR

Funding

CONICET PIP 2022-2024 #11220210100091COMinisterio de Ciencia, Tecnología e Innovación PICT 2019 Nº 3292
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal motoneuron degenerative disease that is associated with demyelination. The

Indexed as

Amyotrophic Lateral SclerosisDisease Models, AnimalMyelin SheathTestosteroneAnimalsExcitatory Amino Acid Transporter 2MaleMiceMicrogliaSpinal CordExcitatory Amino Acid Transporter 2TestosteroneALSanastrozoleandrogensaromatasemyelintestosteroneWobbler mouse

Identifiers

PMID38672445
PMCPMC11048492
OpenAlexW4393486346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.