Evidence map›Paper›PMID 38672440›Full record

ArticleBiomolecules2024

Computational Modeling and Characterization of Peptides Derived from Nanobody Complementary-Determining Region 2 (CDR2) Targeting Active-State Conformation of the β

Milan Sencanski, Sanja Glisic, Valentina Kubale, Marko Cotman, Janez Mavri, Milka Vrecl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Milan SencanskiLaboratory for Plant Molecular Biology, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-7296-3223
Sanja GlisicLaboratory for Bioinformatics and Computational Chemistry, Institute of Nuclear Sciences VINCA, National Institute of Serbia, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-5691-1055
Valentina KubaleInstitute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Marko CotmanInstitute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Janez MavriDepartment of Computational Biochemistry and Drug Design, National Institute of Chemistry, 1000 Ljubljana, Slovenia.ORCID 0000-0002-0767-6367
Milka VreclInstitute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-9968-9228
University of Ljubljana · SIUniversity of Belgrade · RSNational Institute of Chemistry · SI

Funding

Ministry of Education, Science, and Technological Development of the Republic of Serbia 451-03-66/2024-03/200042Ministry of Science, Technological Development and Innovation of the Republic of Serbia 451-03-66/2024-03/200017Slovenian Research and Innovation Agency P1-0012Slovenian Research and Innovation Agency P4-0053
6 · The paper itself

Abstract

This study assessed the suitability of the complementarity-determining region 2 (CDR2) of the nanobody (Nb) as a template for the derivation of nanobody-derived peptides (NDPs) targeting active-state β

Indexed as

PeptidesReceptors, Adrenergic, beta-2Single-Domain AntibodiesAmino Acid SequenceComplementarity Determining RegionsCyclic AMPHumansMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingProtein ConformationComplementarity Determining RegionsCyclic AMPPeptidesReceptors, Adrenergic, beta-2Single-Domain Antibodiesbioinformaticscell-based in vitro assayscomplementary-determining region 2molecular modelingnanobody-derived peptidesβ2-adrenergic receptor

Identifiers

PMID38672440
PMCPMC11048008
OpenAlexW4393357095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.