ArticleAnimals : an open access journal from MDPI2024
Saponin Extracts Utilization as Dietary Additive in Ruminant Nutrition: A Meta-Analysis of In Vivo Studies.
Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Influence of saponin extracts on enteric methane emission and rumen fermentation: a meta-analysis of in vitro experiments.BMC veterinary research · 2026Pooled it
- Evaluation ofFood chemistry: X · 2026Article
- Managing Anti-Nutritional Factors in Plant-Based Feeds: Implications for Herbivore Nutrition and Production.Metabolites · 2026Review
- Nutritional Strategies for Methane, Nitrogen, and Phosphorus Mitigation in Ruminants: Mechanisms, Applications, and Regional Adaptations.Microorganisms · 2026Review
- Synergistic effects ofVeterinary world · 2026Article
- Interactive Effects ofAnimals : an open access journal from MDPI · 2026Article
- Assessment of Moringa oleifera and Clitoria ternatea as non-conventional protein sources: chemical composition, greenhouse gas production, and rumen fermentation.Tropical animal health and production · 2026Article
- Phytochemicals in Ruminant Diets: Mechanistic Insights, Product Quality Enhancement, and Pathways to Sustainable Milk and Meat Production-Invited Review.Animals : an open access journal from MDPI · 2026Review
- Mitigating enteric methane emissions: An overview of methanogenesis, inhibitors and future prospects.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- Meta-Analysis of Incorporating Glucosinolates into Diets and Their Effects on Ruminant Performance, Ruminal Fermentation, Methane Emissions, Milk Composition, and Metabolic Biochemical Attributes.Animals : an open access journal from MDPI · 2025Article
- Advances in Nutritional Manipulation of Rumen Fermentation.Animals : an open access journal from MDPI · 2025Article
- Effects ofAnimals : an open access journal from MDPI · 2025Article
- Mechanisms by which phytogenic extracts enhance livestock reproductive health: current insights and future directions.Frontiers in veterinary science · 2025Review
- Effect of adding citrus flavonoid (Bioflavex) to diet on growth, feed efficiency, rumen histomorphology, carcass traits and meat quality of lambs.Frontiers in veterinary science · 2025Article
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Authors and funding
12 authors.
Funding
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Abstract
The present meta-analysis aimed to determine the underlying effects of different saponins extracted from different sources on the production performance, milk yield, digestibility, rumen fermentation, blood metabolites, and nitrogen utilization of ruminants. A total of 26 papers comprising 66 in vivo studies (148 data points of dietary treatments) were evaluated in the present study. The databases were statistically analyzed using the mixed model procedure of SAS, where experiments considered random effects and tannin-related factors were treated as fixed effects. Statistical procedures were then continued in comparing different sources of saponin extract through Mixed Model analysis, where experiments were also random factors and sources of saponin extract were fixed factors. The evidence revealed in the present meta-analysis that saponin supplementation of up to 40 g/kg DM appears to have no detrimental impact on feed intake across ruminant types, suggesting that it does not significantly affect diet palatability. However, the results indicated that there are species-specific responses to saponin supplementation, particularly in relation to palatability and nutrient absorption efficiency, with larger ruminants being better able to tolerate the bitterness induced by saponin extracts. Furthermore, the study found that saponin extracts can influence nutrient digestibility and rumen fermentation dynamics, with different effects observed in large and small ruminants. While some saponin extracts can enhance average daily weight gain and milk yield, others can have adverse effects, highlighting the importance of considering both saponin sources and animal physiological condition when developing nutritional strategies. Additionally, optimization of ruminant production by utilizing saponin extracts is necessary to avoid negative health implications, such as increased blood creatinine levels. Different saponin extracts utilization in ruminant nutrition and environmental management, have a distinct understanding associated to their various bioactive properties. However, among the saponin sources, saponin extracted from
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