Evidence map›Paper›PMID 38672291›Full record

ArticleAnimals : an open access journal from MDPI2024

Increased Dietary Trp, Thr, and Met Supplementation Improves Performance, Health, and Protein Metabolism of Weaned Piglets under Mixed Management and Poor Housing Conditions.

Joseane Penteado Rosa Gonçalves, Antonio Diego Brandão Melo, Qinnan Yang, Marllon José Karpeggiane de Oliveira, Danilo Alves Marçal, Manoela Trevisan Ortiz, Pedro Righetti Arnaut, Ismael França, Graziela Alves da Cunha Valini, Cleslei Alisson Silva and 8 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Joseane Penteado Rosa GonçalvesDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Antonio Diego Brandão MeloDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Qinnan YangDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Marllon José Karpeggiane de OliveiraDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Danilo Alves MarçalDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Manoela Trevisan OrtizDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Pedro Righetti ArnautDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Ismael FrançaDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.ORCID 0000-0002-0534-6145
Graziela Alves da Cunha ValiniDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.ORCID 0000-0002-8933-5100
Cleslei Alisson SilvaDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.
Nate KorthDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Natasha PavlovikjHolland Computing Center, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Paulo Henrique Reis Furtado CamposDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-900, Brazil.ORCID 0000-0002-5031-0790
Henrique Gastmann BrandEvonik Brazil Ltd.a, São Paulo 04711-904, Brazil.
John Kyaw HtooEvonik Operations GmbH, 63457 Hanau, Germany.ORCID 0000-0001-5632-5689
João Carlos Gomes-NetoDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Andrew K BensonDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0001-6330-0252
Luciano HauschildDepartment of Animal Science, School of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), Campus Jaboticabal, São Paulo 14884-900, Brazil.

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/15559-7
6 · The paper itself

Abstract

A sanitary challenge was carried out to induce suboptimal herd health while investigating the effect of amino acids supplementation on piglet responses. Weaned piglets of high sanitary status (6.33 ± 0.91 kg of BW) were distributed in a 2 × 2 factorial arrangement into two similar facilities with contrasting sanitary conditions and two different diets. Our results suggest that increased Trp, Thr, and Met dietary supplementation could support the immune systems of piglets under a sanitary challenge. In this manner, AA+ supplementation improved the performance and metabolism of piglets under mixed management and poor sanitary conditions. No major temporal microbiome changes were associated with differences in performance regardless of sanitary conditions or diets. Since piglets often become mixed in multiple-site production systems and facility hygiene is also often neglected, this study suggests that increased Trp, Thr, and Met (AA+) dietary supplementation could contribute to mitigating the side effects of these harmful risk factors in modern pig farms.

Indexed as

amino acidshaptoglobinimmune challengemicrobiomemultiple origins

Identifiers

PMID38672291
PMCPMC11047353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.