Evidence map›Paper›PMID 38672234›Full record

ReviewBiomedicines2024

Two Signaling Modes Are Better than One: Flux-Independent Signaling by Ionotropic Glutamate Receptors Is Coming of Age.

Valentina Brunetti, Teresa Soda, Roberto Berra-Romani, Giovambattista De Sarro, Germano Guerra, Giorgia Scarpellino, Francesco Moccia

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Metabotropic NMDAR Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Valentina BrunettiLaboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", 27110 Pavia, Italy.
Teresa SodaDepartment of Health Sciences, School of Medicine and Surgery, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-7728-6815
Roberto Berra-RomaniDepartment of Biomedicine, School of Medicine, Benemérita Universidad Autónoma de Puebla, Puebla 72410, Mexico.ORCID 0000-0003-4884-0925
Giovambattista De SarroDepartment of Health Sciences, School of Medicine and Surgery, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-7629-6579
Germano GuerraDepartment of Medicine and Health Science "Vincenzo Tiberio", School of Medicine and Surgery, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-4342-962X
Giorgia ScarpellinoLaboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", 27110 Pavia, Italy.ORCID 0000-0003-1673-6146
Francesco MocciaDepartment of Medicine and Health Science "Vincenzo Tiberio", School of Medicine and Surgery, University of Molise, 86100 Campobasso, Italy.
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITMagna Graecia University · ITUniversity of Molise · ITBenemérita Universidad Autónoma de Puebla · MX

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías CVU121216European Commission's FESR FSE 2014-2020 and POR CALABRIA FESR AZIONE 1.5.1 "Support for research infrastructures considered critical/crucial for regional systems" Nuova Piattaforma di Farmacologia Integrata e Tecnologie AvanzateMinistry of University and Research (MUR), National Recovery and Resilience Plan (NRRP) project MNESYS (PE0000006) - A Multiscale integrated approach to the study of the nervous sys-tem in health and disease (DN. 1553 11.10.2022)
6 · The paper itself

Abstract

Glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic transmission can be mediated by ionotropic glutamate receptors (iGluRs), which mediate rapid synaptic depolarization that can be associated with Ca

Indexed as

AMPA receptorsflux-independent signalingglutamateionotropic glutamate receptorskainate receptorsNMDA receptorsnon-canonical signaling

Identifiers

PMID38672234
PMCPMC11048239
OpenAlexW4394837804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.