Evidence map›Paper›PMID 38671953›Full record

ArticleBrain sciences2024

Machine Learning-Assisted Classification of Paraffin-Embedded Brain Tumors with Raman Spectroscopy.

Gilbert Georg Klamminger, Laurent Mombaerts, Françoise Kemp, Finn Jelke, Karoline Klein, Rédouane Slimani, Giulia Mirizzi, Andreas Husch, Frank Hertel, Michel Mittelbronn and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Gilbert Georg KlammingerDepartment of General and Special Pathology, Saarland University (USAAR), 66424 Homburg, Germany.ORCID 0000-0001-5358-2751
Laurent MombaertsLuxembourg Center of Neuropathology (LCNP), 3555 Dudelange, Luxembourg.
Françoise KempLuxembourg Center of Neuropathology (LCNP), 3555 Dudelange, Luxembourg.
Finn JelkeNational Center of Neurosurgery, Centre Hospitalier de Luxembourg (CHL), 1210 Luxembourg, Luxembourg.
Karoline KleinNational Center of Neurosurgery, Centre Hospitalier de Luxembourg (CHL), 1210 Luxembourg, Luxembourg.
Rédouane SlimaniDoctoral School in Science and Engineering (DSSE), University of Luxembourg (UL), 4362 Esch-sur-Alzette, Luxembourg.
Giulia MirizziNational Center of Neurosurgery, Centre Hospitalier de Luxembourg (CHL), 1210 Luxembourg, Luxembourg.
Andreas HuschNational Center of Neurosurgery, Centre Hospitalier de Luxembourg (CHL), 1210 Luxembourg, Luxembourg.ORCID 0000-0001-9404-5127
Frank HertelNational Center of Neurosurgery, Centre Hospitalier de Luxembourg (CHL), 1210 Luxembourg, Luxembourg.
Michel MittelbronnLuxembourg Center of Neuropathology (LCNP), 3555 Dudelange, Luxembourg.
Felix B Kleine BorgmannNational Center of Pathology (NCP), Laboratoire National de Santé (LNS), 3555 Dudelange, Luxembourg.ORCID 0000-0001-5689-6860
Centre Hospitalier de Luxembourg · LULaboratoire National de Santé · LUUniversity of Luxembourg · LU

Funding

Fondation Cancer (Luxembourg) and Luxembourg National Research Fond FNR PEARL P16/BM/11192868
6 · The paper itself

Abstract

Raman spectroscopy (RS) has demonstrated its utility in neurooncological diagnostics, spanning from intraoperative tumor detection to the analysis of tissue samples peri- and postoperatively. In this study, we employed Raman spectroscopy (RS) to monitor alterations in the molecular vibrational characteristics of a broad range of formalin-fixed, paraffin-embedded (FFPE) intracranial neoplasms (including primary brain tumors and meningiomas, as well as brain metastases) and considered specific challenges when employing RS on FFPE tissue during the routine neuropathological workflow. We spectroscopically measured 82 intracranial neoplasms on CaF

Indexed as

artificial intelligencebrain metastasisgliomasmachine learningmeningiomasRaman spectroscopyrandom forest classificationtumor necrosisvibrational spectroscopy

Identifiers

PMID38671953
PMCPMC11048578
OpenAlexW4393142103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.