Evidence map›Paper›PMID 38671902›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Nrf2 Plays a Key Role in Erythropoiesis during Aging.

Serge Cedrick Toya Mbiandjeu, Angela Siciliano, Alessandro Mattè, Enrica Federti, Massimiliano Perduca, Davide Melisi, Immacolata Andolfo, Angela Amoresano, Achille Iolascon, Maria Teresa Valenti and 10 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Serge Cedrick Toya MbiandjeuDepartment of Medicine, University of Verona, 37134 Verona, Italy.
Angela SicilianoDipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Alessandro MattèDepartment of Medicine, University of Verona, 37134 Verona, Italy.
Enrica FedertiDipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Massimiliano PerducaDepartment of Biotechnology, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-8291-0523
Davide MelisiDepartment of Medicine, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-4031-7585
Immacolata AndolfoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.
Angela AmoresanoDepartment of Chimical Sciences, University Federico II, 80138 Naples, Italy.
Achille IolasconDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.ORCID 0000-0002-9558-0356
Maria Teresa ValentiDepartment of Neuroscience, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-1166-8033
Francesco TurriniDepartment of Oncology, University of Torino, 10124 Torino, Italy.
Michele BoviDepartment of Biotechnology, University of Verona, 37134 Verona, Italy.
Arianna PisaniDepartment of Biotechnology, University of Verona, 37134 Verona, Italy.
Antonio RecchiutiDepartment of Medical, Oral, and Biotechnology Science, "G. d'Annunzio" University Chieti-Pescara, 66013 Chieti, Italy.ORCID 0000-0002-1409-5261
Domenico MattoscioDepartment of Medical, Oral, and Biotechnology Science, "G. d'Annunzio" University Chieti-Pescara, 66013 Chieti, Italy.ORCID 0000-0002-2149-2855
Veronica RiccardiDipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Luca Dalle CarbonareDipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-3263-6671
Carlo BrugnaraDepartment of Laboratory Medicine, Boston Children's Hospital, Boston, MA 02114, USA.
Narla MohandasNew York Blood Center Enterprises, New York, NY 10065, USA.
Lucia De FranceschiDipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-7093-777X
University of Verona · ITCeinge Biotecnologie Avanzate (Italy) · ITUniversity of Chieti-Pescara · ITBoston Children's Hospital · USNew York Blood Center · USUniversity of Turin · IT

Funding

Ministero dell'Istruzione e del Merito 2020Z22PM7
6 · The paper itself

Abstract

Aging is characterized by increased oxidation and reduced efficiency of cytoprotective mechanisms. Nuclear factor erythroid-2-related factor (Nrf2) is a key transcription factor, controlling the expression of multiple antioxidant proteins. Here, we show that Nrf2

Indexed as

astaxanthinATF6autophagyGADD34ineffective erythropoiesisnanoparticlesoxidationPLGAred cellsUPR system

Identifiers

PMID38671902
PMCPMC11047311
OpenAlexW4394754240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.