Evidence map›Paper›PMID 38671818›Full record

ArticleBioengineering (Basel, Switzerland)2024

Micro-Computed Tomography Analysis of Peri-Implant Bone Defects Exposed to a Peri-Implantitis Microcosm, with and without Bone Substitute, in a Rabbit Model: A Pilot Study.

Camila Panes, Iván Valdivia-Gandur, Carlos Veuthey, Vanessa Sousa, Mariano Del Sol, Víctor Beltrán

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Camila PanesCenter of Excellence in Morphological and Surgical Studies (CEMyQ), School of Medicine, University of La Frontera, Temuco 4780000, Chile.ORCID 0000-0002-2092-5719
Iván Valdivia-GandurBiomedical Department, Universidad de Antofagasta, Antofagasta 1270300, Chile.ORCID 0000-0002-7835-2001
Carlos VeutheyCenter of Excellence in Morphological and Surgical Studies (CEMyQ), School of Medicine, University of La Frontera, Temuco 4780000, Chile.
Vanessa SousaPeriodontology and Periodontal Medicine, Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, Kings College London, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.ORCID 0000-0003-3772-3221
Mariano Del SolCenter of Excellence in Morphological and Surgical Studies (CEMyQ), School of Medicine, University of La Frontera, Temuco 4780000, Chile.ORCID 0000-0003-3686-6757
Víctor BeltránFaculty of Dentistry, Universidad de La Frontera, Temuco 4780000, Chile.ORCID 0000-0001-6046-821X
Universidad de La Frontera · CLKing's College London · GBUniversidad de Antofagasta · CL

Funding

Fondo de Fomento al Desarrollo Científico y Tecnológico (FONDEF) 2 2365 4400
6 · The paper itself

Abstract

Peri-implantitis is an inflammatory condition characterized by inflammation in the peri-implant connective tissue and a progressive loss of supporting bone; it is commonly associated with the presence of biofilms on the surface of the implant, which is an important factor in the development and progression of the disease. The objective of this study was to evaluate, using micro-CT, the bone regeneration of surgically created peri-implant defects exposed to a microcosm of peri-implantitis. Twenty-three adult New Zealand white rabbits were included in the study. Bone defects of 7 mm diameter were created in both tibiae, and a cap-shaped titanium device was placed in the center, counter-implanted with a peri-implantitis microcosm. The bone defects received a bone substitute and/or a resorbable synthetic PLGA membrane, according to random distribution. Euthanasia was performed 15 and 30 days postoperatively. Micro-CT was performed on all samples to quantify bone regeneration parameters. Bone regeneration of critical defects occurred in all experimental groups, with a significantly greater increase in cases that received bone graft treatment (

Indexed as

animal modelcritical size defectsdental implantmicrocomputed tomographyperi-implant bone defectsperi-implantitis

Identifiers

PMID38671818
PMCPMC11048142
OpenAlexW4394955807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.