ArticleBioengineering (Basel, Switzerland)2024
Tuning Mechanical Characteristics and Permeability of Alginate Hydrogel by Polyvinyl Alcohol and Deep Eutectic Solvent Addition.
Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Alginate-PVA interpenetrating network nanogels: a pH-responsive carrier for thermal stabilization and sustained release of phycocyanin.Food chemistry: X · 2026Article
- Formulation and evaluation of hydrogel based on Brazilian propolis ethanol extract for promoting diabetic wound healing.BMC biotechnology · 2026Article
- PRP-loaded pH-responsive hydrogel for the amelioration of ventricular remodeling following myocardial infarction.Materials today. Bio · 2026Article
- Harnessing the potential of deep eutectic solvents in biocatalysis: design strategies using COFrontiers in chemistry · 2024Article
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Authors and funding
3 authors.
Funding
Abstract
Alginate-based hydrogels are widely utilized for various applications, including enzyme immobilization and the development of drug delivery systems, owing to their advantageous characteristics, such as low toxicity, high availability and cost-effectiveness. However, the broad applicability of alginate hydrogels is hindered by their limited mechanical and chemical stability, as well as their poor permeability to hydrophobic molecules. In this study, we addressed the mechanical properties and chemical resistance of alginate hydrogels in a high-pKa environment by the copolymerization of alginate with polyvinyl alcohol (PVA). The addition of PVA resulted in a threefold improvement in the shear modulus of the copolymeric hydrogel, as well as enhanced chemical resistance to (
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