Evidence map›Paper›PMID 38671640›Full record

ArticleChildren (Basel, Switzerland)2024

Diagnosis and Management of Congenital H-Type Tracheoesophageal Fistula: Results of a National Survey.

Cecilia Morchio, Alba Ganarin, Andrea Conforti, Ernesto Leva, Giovanni Gaglione, Gaia Brenco, Elisa Zambaiti, Salvatore Fabio Chiarenza, Tamara Caldaro, Maurizio Cheli and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 15 institutions in 1 country.

Cecilia MorchioSchool of Pediatric Surgery, University of Florence, 50100 Florence, Italy.
Alba GanarinPediatric Surgery Unit, Ca' Foncello Hospital, 31100 Treviso, Italy.
Andrea ConfortiNeonatal Surgery Unit, Medical and Surgical Department of Fetus-Newborn-Infant, Bambino Gesù Children's Hospital, IRCCS, 00100 Rome, Italy.
Ernesto LevaPediatric Surgery Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, University of Milan, 20100 Milan, Italy.
Giovanni GaglioneUOC Pediatric Surgery Unit, AORN Santobono-Pausilipon, 80100 Naples, Italy.
Gaia BrencoPediatric Surgery Unit, IRCCS Giannina Gaslini's Hospital, 16100 Genova, Italy.
Elisa ZambaitiDepartment of Pediatric General Surgery, Regina Margherita Children's Hospital, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, 10100 Turin, Italy.ORCID 0000-0002-9610-1708
Salvatore Fabio ChiarenzaDepartment of Pediatric Surgery, San Bortolo Hospital, 36100 Vicenza, Italy.
Tamara CaldaroDigestive Endoscopy and Surgery Unit, Bambino Gesu Children's Hospital, IRCCS, 00100 Rome, Italy.
Maurizio CheliPediatric Surgery Unit, Ospedale Papa Giovanni XXIII, 24100 Bergamo, Italy.
Giovanni BoroniDepartment of Paediatric Surgery, ASST Spedali Civili di Brescia, 25100 Brescia, Italy.ORCID 0000-0003-3341-5379
Elena Sofia MarcandellaPaediatric Surgery Unit, Women's and Children's Health Department, University of Padua, 35100 Padua, Italy.ORCID 0009-0003-6864-0709
Giovanna RiccipetitoniDepartment of Paediatric Surgery, "V. Buzzi" Children's Hospital, 20100 Milan, Italy.
Sebastiano CacciaguerraDepartment of Pediatric Surgery, Ospedale Garibaldi-Nesima, 95100 Catania, Italy.
Vincenzo Di BenedettoDepartment of Pediatric Surgery, G. Rodolico-San Marco Hospital, 95100 Catania, Italy.
Valerio GentilinoDivision of Pediatric Surgery, Woman and Child Department, "Filippo Del Ponte" Hospital, ASST Sette Laghi, 21100 Varese, Italy.
Gabriele LisiPediatric Surgery Unit, Santo Spirito Hospital, University of Chieti-Pescara, 65100 Pescara, Italy.ORCID 0000-0002-7590-9505
Francesco MoriniDepartment of Maternal and Child Health and Urological Sciences, La Sapienza University, 00100 Rome, Italy.
Paola MidrioPediatric Surgery Unit, Ca' Foncello Hospital, 31100 Treviso, Italy.
Bambino Gesù Children's Hospital · ITCa' Foncello Hospital · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITIstituto Giannina Gaslini · ITOspedale Filippo Del Ponte Varese · ITOspedale Garibaldi · ITOspedale Papa Giovanni XXIII · ITOspedale San Bortolo · ITSapienza University of Rome · ITUniversity of Chieti-Pescara · ITUniversity of Florence · ITUniversity of Milan · ITUniversity of Padua · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital h-type tracheoesophageal fistula (H-TEF) without esophageal atresia (EA) represents about 4% of congenital esophageal anomalies. The diagnosis is challenging, and surgery is considered curative. The aim was to report a national survey on the diagnosis, management, and outcome of patients with congenital H-TEF.

methodsFollowing approval of the Italian Society of Pediatric Surgery, a survey was sent to all Pediatric Surgery Units to retrospectively collect H-TEF treated in the period 2010-2022. Descriptive analysis was performed, and results are given as prevalence, mean ± standard deviation (SD), or median and interquartile range (IQR).

resultsThe survey was sent to 65 units. Seventeen responded with one or more cases; 78 patients were diagnosed with H-TEF during the study period. Associated malformations were present in 43%, mostly cardiac (31%). The most frequent symptoms were cough (36%), bronchopneumonia (24%), and dysphagia (19%). H-TEF was detected by tracheobronchoscopy (90%), and/or upper GI (58%), and/or esophagoscopy (32%). The median age at diagnosis was 23 days (1 day-18 years). The most common approach was cervicotomy (76%), followed by thoracoscopy (14%) and thoracotomy (9%). The fistula underwent ligation and section of the fistula in 90% of the patients and clip closure and section in 9%. In one patient, the fistula was cauterized endoscopically. H-TEF preoperative cannulation was performed in 68% of cases, and a drain was placed in 26%. One month after surgery, 13% of the patients had mild persisting symptoms, mainly hypophonia. Recurrence occurred in 5%, and a second recurrence occurred in 1%.

conclusionsH-TEF prevalence was six cases/year, consistent with the expected rate of five cases/year in our country. The diagnosis was challenging, sometimes delayed, and, in most patients, required multiple examinations. Fistula ligation and section through cervicotomy were the most frequent treatment. Long-term outcomes are good, and recurrence is a rare event.

Indexed as

congenital tracheoesophageal fistulah-type esophageal atresiatype E esophageal atresia

Identifiers

PMID38671640
PMCPMC11048938
OpenAlexW4393408895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.