Evidence map›Paper›PMID 38671474›Full record

ReviewJournal of nanobiotechnology2024

Carbon dots as a novel photosensitizer for photodynamic therapy of cancer and bacterial infectious diseases: recent advances.

Lingxiang Sun, Yifan Zhao, Hongyi Peng, Jian Zhou, Qingmei Zhang, Jingyu Yan, Yingyu Liu, Susu Guo, Xiuping Wu, Bing Li

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
19.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 104 citations in OpenAlex.

  1. Review
  2. Article
  3. Nitrogen-Doped Carbon Dot/TiOBiomolecules · 2026
    Article
  4. Blue light activated nitrogen doped poly floral carbon quantum dots: multifunctional agent for anti-microbial and anti-cancer photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lingxiang Sun *School and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China.
Yifan Zhao *School and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China.
Hongyi Peng *School and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China.
Jian ZhouLaboratory for Oral and General Health Integration and Translation, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100069, China.
Qingmei ZhangTaiyuan University of Science and Technology, Taiyuan, China.
Jingyu YanSchool and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China.
Yingyu LiuSchool and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China.
Susu GuoSchool and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China.
Xiuping WuSchool and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China. 77wxp@163.com.
Bing LiSchool and Hospital of Stomatology, Shanxi Medical University, Taiyuan, China. libing1975vip@163.com.
Shanxi Medical University · CNCapital Medical University · CNTaiyuan University of Science and Technology · CN

Funding

Shanxi Provincial Science and Technology Innovation Key Talent Team Project No. 202204051002034the Central Government Guided Local Science and Technology Development Funds (Transfer and Transformation of Scientific and Technological Achievements) Project No. YDZJSX2022C029the Creation of hydroxyapatite-loaded chalcogenide quantum dot fluorescent probes and study of FLISA method for saliva detection, Shanxi Province Returned Overseas Students Research Project No. 2022-120the Development and application demonstration of new dental nanocomposite structural materials, Shanxi Province Key Research and Development Program No. 202102130501002
6 · The paper itself

Abstract

Carbon dots (CDs) are novel carbon-based nanomaterials that have been used as photosensitizer-mediated photodynamic therapy (PDT) in recent years due to their good photosensitizing activity. Photosensitizers (PSs) are main components of PDT that can produce large amounts of reactive oxygen species (ROS) when stimulated by light source, which have the advantages of low drug resistance and high therapeutic efficiency. CDs can generate ROS efficiently under irradiation and therefore have been extensively studied in disease local phototherapy. In tumor therapy, CDs can be used as PSs or PS carriers to participate in PDT and play an extremely important role. In bacterial infectious diseases, CDs exhibit high bactericidal activity as CDs are effective in disrupting bacterial cell membranes leading to bacterial death upon photoactivation. We focus on recent advances in the therapy of cancer and bacteria with CDs, and also briefly summarize the mechanisms and requirements for PSs in PDT of cancer, bacteria and other diseases. We also discuss the role CDs play in combination therapy and the potential for future applications against other pathogens.

Indexed as

Bacterial InfectionsCarbonNeoplasmsPhotochemotherapyPhotosensitizing AgentsQuantum DotsAnimalsHumansReactive Oxygen SpeciesCarbonPhotosensitizing AgentsReactive Oxygen SpeciesAntibacterial resistanceCarbon dotsCombined treatmentNanotechnologyPhotodynamic therapy

Identifiers

PMID38671474
PMCPMC11055261
OpenAlexW4395662997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.