Evidence map›Paper›PMID 38671412›Full record

ArticleBMC pregnancy and childbirth2024

Health education to promote knowledge about sickle cell disease and newborn screening in pregnant women: a community-based pilot study using the healthy beginning initiative.

Osita U Ezenwosu, John O Olawepo, Lorraine J Lacroix-Willliamson, Ijeoma U Itanyi, Amaka Ogidi, Tonia C Onyeka, Madeline Gully, Maisha Gregory, Janis L Breeze, Stephanie Ibemere and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Osita U EzenwosuCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria. osita.ezenwosu@unn.edu.ng.
John O OlawepoCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria.
Lorraine J Lacroix-WillliamsonDepartment of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA, USA.
Ijeoma U ItanyiCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria.
Amaka OgidiCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria.
Tonia C OnyekaCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria.
Madeline GullyDepartment of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA, USA.
Maisha GregorySchool of Nursing, Bouvé College of Health Sciences, Northeastern University, Boston, USA.
Janis L BreezeTufts Clinical and Translational Science Institute, Institute for Clinical Research and Health Policy Studies, Tufts University, Tufts Medical Center, Boston, MA, USA.
Stephanie IbemereDuke University School of Nursing, Duke Global Health Institute, Durham, NC, USA.
Ngozi Idemili-AronuCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria.
Beth E MolnarDepartment of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA, USA.
Echezona E EzeanolueCenter for Translation and Implementation Research, University of Nigeria, Enugu, Nigeria.
University of Nigeria · NGNortheastern University · USDuke Institute for Health Innovation · USTufts University · US

Funding

Institute for Health Equity and Social Justice Research, Northeastern University, Boston, USA. CTAIR UNN and Healthy Sunrise Foundation, Las Vegas, USA. IHESJR_Olawepo_2021-23
6 · The paper itself

Abstract

backgroundPregnancy presents a critical period for any maternal and child health intervention that may impact the health of the newborn. With low antenatal care attendance by pregnant women in health facilities in Nigeria, community-based programs could enable increased reach for health education about sickle cell disease (SCD) and newborn screening (NBS) among pregnant women. This pilot study aimed to assess the effect of education on the knowledge about SCD and NBS among pregnant women using the Healthy Beginning Initiative, a community-based framework.

methodsA pre-post study design was used to evaluate knowledge of SCD and NBS in a convenience sample of 89 consenting pregnant women from three communities. Participants were given surveys prior to and following completion of a health education session. McNemar's test was used to compare the proportion of participants with correct responses. The level of significance was taken as p < 0.05.

resultsCompared to pre-test values, post-test values showed that participants understood that SCD is hereditary (93.3% vs. 69.7%), both parents must have at least one gene for someone to have SCD (98.9% vs. 77.5) and blood test is the right way to know if one has SCD (98.8% vs. 78.7%). Also, a large proportion of participants (post-test ~ 89.9%; compared to pre-test ~ 23.6%) understood that the chance of conceiving a child with SCD was 25% for a couple with the sickle cell trait (SCT). Knowledge of the possibility of diagnosing SCD shortly after birth was highly increased in the post test phase of the study when compared to the pre-test phase (93.3% vs. 43.9%, respectively). Concerning the overall knowledge scores, those with high level of knowledge significantly increase from 12.6% pretest to 87.4% posttest (p = 0.015).

conclusionThe health education intervention was associated with significant improvement on almost all measures of SCD knowledge. Focused health education for pregnant women using community structures can improve knowledge of SCD and NBS.

Indexed as

Anemia, Sickle CellHealth EducationHealth Knowledge, Attitudes, PracticeNeonatal ScreeningAdultFemaleHumansInfant, NewbornNigeriaPilot ProjectsPregnancyPregnant PeoplePrenatal CareYoung AdultCommunity-based interventionHealth educationHealthy beginning InitiativeNewborn screeningPregnant womenSickle cell disease

Identifiers

PMID38671412
PMCPMC11046861
OpenAlexW4395699574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.