ArticleNature communications2024
Human connectome topology directs cortical traveling waves and shapes frequency gradients.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Traveling waves along the cortical depth reflect structured synaptic inputs.Research square · 2026Article
- Article
- Sub-second fluctuations between top-down and bottom-up modes distinguish diverse human brain states.Current biology : CB · 2026Article
- Hidden Spirals Reveal the Neurocomputational Mechanisms of Traveling Waves in Human Memory.bioRxiv : the preprint server for biology · 2026Article
- A digital twin approach for simultaneous reconstruction of brain anatomy and dynamics from neural data.PLOS digital health · 2026Article
- Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dynamical mechanisms for coordinating long-term working memory based on the precision of spike-timing in cortical neurons.Biological cybernetics · 2026Review
- Three parsimonious spatiotemporal patterns in cerebellum reveal individual traits in function and behavior.Nature communications · 2026Article
- Propofol-induced loss of responsiveness reorganizes cortical traveling waves in the human brain.bioRxiv : the preprint server for biology · 2026Article
- A geometry aware framework enhances noninvasive mapping of whole human brain dynamics.Nature biomedical engineering · 2026Article
- Psilocybin shapes the slow, global propagation of brain activity over the cortical layout of 5HT2a receptors.Communications biology · 2026Article
- Hierarchical whole-brain modeling of critical synchronization dynamics in the human brain.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The frequency response of networks as open systems.Nature communications · 2026Article
- Oscillatory dynamics as the coordination layer of the organism: waves, Markov blankets, and the virtual space of cognition.Frontiers in neuroscience · 2026Article
- The turbulent brain: Modeling vortex interactions for understanding human cognition.Network neuroscience (Cambridge, Mass.) · 2026Article
- Human cortical dynamics reflect graded contributions of local geometry and network topography.Nature communications · 2025Article
- Article
- Brain-Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety-Like Behaviors in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Locally Induced Traveling Waves Generate Globally Observable Traveling Waves.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Traveling waves link human visual and frontal cortex during working memory-guided behavior.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traveling waves and neural oscillation frequency gradients are pervasive in the human cortex. While the direction of traveling waves has been linked to brain function and dysfunction, the factors that determine this direction remain elusive. We hypothesized that structural connectivity instrength gradients - defined as the gradually varying sum of incoming connection strengths across the cortex - could shape both traveling wave direction and frequency gradients. We confirm the presence of instrength gradients in the human connectome across diverse cohorts and parcellations. Using a cortical network model, we demonstrate how these instrength gradients direct traveling waves and shape frequency gradients. Our model fits resting-state MEG functional connectivity best in a regime where instrength-directed traveling waves and frequency gradients emerge. We further show how structural subnetworks of the human connectome generate opposing wave directions and frequency gradients observed in the alpha and beta bands. Our findings suggest that structural connectivity instrength gradients affect both traveling wave direction and frequency gradients.
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