Evidence map›Paper›PMID 38670064›Full record

ReviewCell2024

From periphery to center stage: 50 years of advancements in innate immunity.

Susan Carpenter, Luke A J O'Neill

Erratum issuedAbstract readReviewHistorical Article
In one paragraph

Review in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Gut microbes · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Innate immunity: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Regulation of Innate Immune Signaling by Autophagy.International journal of molecular sciences · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Innate immune signalling in the adipocyte.Journal of biochemistry · 2026
    Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Susan CarpenterUniversity of California Santa Cruz, 1156 High St., Santa Cruz, CA 95064, USA. Electronic address: sucarpen@ucsc.edu.
Luke A J O'NeillSchool of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. Electronic address: laoneill@tcd.ie.

Funding

High throughput functional characterization of lncRNAs in macrophage biologyR35GM137801 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CARPENTER, SUSAN · 2020 to 2024
$2.2M
Determining the conserved molecular mechanisms contributing to inflammation during SepsisR01AI148413 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CARPENTER, SUSAN · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI148413NIGMS NIH HHS R35 GM137801
6 · The paper itself

Abstract

Over the past 50 years in the field of immunology, something of a Copernican revolution has happened. For a long time, immunologists were mainly concerned with what is termed adaptive immunity, which involves the exquisitely specific activities of lymphocytes. But the other arm of immunity, so-called "innate immunity," had been neglected. To celebrate Cell's 50

Indexed as

Allergy and ImmunologyImmunity, InnateAdaptive ImmunityAnimalsHistory, 20th CenturyHistory, 21st CenturyHumans

Identifiers

PMID38670064
PMCPMC11060700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.