ArticleScience advances2024
Low-dimensional criticality embedded in high-dimensional awake brain dynamics.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is criticality a unified setpoint of brain function?Neuron · 2025Pooled it
- Critical neuronal avalanches arise from excitation-inhibition balanced spontaneous activity.iScience · 2026Article
- Whisker stimulation reinforces a resting-state network in the barrel cortex: Nested oscillations and avalanches.PLoS computational biology · 2026Article
- Unifying theories in high-dimensional biophysics: approaches, challenges and opportunities.NPJ systems biology and applications · 2026Article
- Hierarchical whole-brain modeling of critical synchronization dynamics in the human brain.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Emergent critical oscillations in motor cortex of Parkinson's patients.bioRxiv : the preprint server for biology · 2026Article
- State-Dependent Dissociation of Shared Input and Directed Information Flow in the Visual Cortex.bioRxiv : the preprint server for biology · 2026Article
- The role of high-amplitude bursts of high-gamma activity in naturalistic speech and music listening.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Two views of the brain are reconciled by a unifying principle of maximal information processing.bioRxiv : the preprint server for biology · 2025Article
- Brain-wide organization of intrinsic timescales at single-neuron resolution.bioRxiv : the preprint server for biology · 2025Article
- Hierarchy of Chaotic Dynamics in Random Modular Networks.Physical review letters · 2025Article
- A mechanism for the emergence of low-dimensional structures in brain dynamics.NPJ systems biology and applications · 2025Article
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5 authors.
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Abstract
Whether cortical neurons operate in a strongly or weakly correlated dynamical regime determines fundamental information processing capabilities and has fueled decades of debate. We offer a resolution of this debate; we show that two important dynamical regimes, typically considered incompatible, can coexist in the same local cortical circuit by separating them into two different subspaces. In awake mouse motor cortex, we find a low-dimensional subspace with large fluctuations consistent with criticality-a dynamical regime with moderate correlations and multi-scale information capacity and transmission. Orthogonal to this critical subspace, we find a high-dimensional subspace containing a desynchronized dynamical regime, which may optimize input discrimination. The critical subspace is apparent only at long timescales, which explains discrepancies among some previous studies. Using a computational model, we show that the emergence of a low-dimensional critical subspace at large timescales agrees with established theory of critical dynamics. Our results suggest that the cortex leverages its high dimensionality to multiplex dynamical regimes across different subspaces.
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