Evidence map›Paper›PMID 38669326›Full record

ArticleScience advances2024

Dual and opposing roles for the kinesin-2 motor, KIF17, in Hedgehog-dependent cerebellar development.

Bridget Waas, Brandon S Carpenter, Nicole E Franks, Olivia Q Merchant, Kristen J Verhey, Benjamin L Allen

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Regulation of kinesin-2 motility by its β-hairpin motif.Nature structural & molecular biology · 2025
    Article
  2. The intraflagellar transport cycle.Nature reviews. Molecular cell biology · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bridget WaasDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-1581-5985
Brandon S CarpenterDepartment of Molecular and Cellular Biology, College of Science and Mathematics, Kennesaw State University, Kennesaw, GA, 30061, USA.ORCID 0000-0001-9939-1926
Nicole E FranksDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-0826-0061
Olivia Q MerchantDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Kristen J VerheyDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Benjamin L AllenDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-2323-8313
University of Michigan · USKennesaw State University · US

Funding

Kinesin Motors and Microtubule-based TraffickingR35GM131744 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kristen J. Verhey · 2019 to 2026
$6.3M
NIGMS NIH HHS R35 GM131744
6 · The paper itself

Abstract

While the kinesin-2 motors KIF3A and KIF3B have essential roles in ciliogenesis and Hedgehog (HH) signal transduction, potential role(s) for another kinesin-2 motor, KIF17, in HH signaling have yet to be explored. Here, we investigated the contribution of KIF17 to HH-dependent cerebellar development, where

Indexed as

CerebellumHedgehog ProteinsKinesinsNervous System MalformationsPurkinje CellsAnimalsCell ProliferationDevelopmental DisabilitiesGene Expression Regulation, DevelopmentalMiceMice, KnockoutNeural Stem CellsSignal TransductionZinc Finger Protein GLI1Hedgehog ProteinsKIF17 protein, mouseKinesinsZinc Finger Protein GLI1

Identifiers

PMID38669326
PMCPMC11051677
OpenAlexW4395676915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.