ArticleScience advances2024
Anisotropic Liesegang pattern for the nonlinear elastic biomineral-hydrogel complex.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Deep hydroxyapatite deposition in porous poly(ethylene glycol) sponge hydrogel via optimized and simplified approach.Science and technology of advanced materials · 2026Article
- Gel-Gel Interface Engineering for the Synthesis of Anisotropic Hydrogels with Designable Polymer Orientations.Advanced materials (Deerfield Beach, Fla.) · 2025Article
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Authors and funding
16 authors.
Funding
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Abstract
The Liesegang pattern is a beautiful natural anisotropic patterning phenomenon observed in rocks and sandstones. This study reveals that the Liesegang pattern can induce nonlinear elasticity. Here, a Liesegang-patterned complex with biomineral-hydrogel repetitive layers is prepared. This Liesegang-patterned complex is obtained only when the biomineralization is performed under the supersaturated conditions. The Liesegang-patterned complex features a nonlinear elastic response, whereas a complex with a single biomineral shell shows a linear behavior, thus demonstrating that the Liesegang pattern is essential in achieving nonlinear elasticity. The stiff biomineral layers have buffered the concentrated energy on behalf of soft hydrogels, thereby exposing the hydrogel components to reduced stress and, in turn, enabling them to perform the elasticity continuously. Moreover, the nonlinear elastic Liesegang-patterned complex exhibits excellent stress relaxation to the external loading, which is the biomechanical characteristic of cartilage. This stress relaxation allows the bundle of fiber-type Liesegang-patterned complex to endure greater deformation.
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Registered trials
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