Evidence map›Paper›PMID 38668998›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2024

An Analysis of the Distribution of Direct Cost of Diabetes Care in Selected Districts in Italy.

Francesco Saverio Mennini, Paolo Sciattella, Andrea Marcellusi, Fausto Bartolini, Francesca Futura Bernardi, Fleur Levrat-Guillen, Marianna Cozzolino, Massimo Di Gennaro, Roberta Giordana, Marianna Giustozzi and 1 more

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Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Criteria for Personalised Choice of a Continuous Glucose Monitoring System: An Expert Opinion.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco Saverio MenniniEconomic Evaluation and HTA (EEHTA), CEIS, DEF, Faculty of Economics, University of Rome "Tor Vergata", Rome, Italy. f.mennini@uniroma2.it.
Paolo SciattellaEconomic Evaluation and HTA (EEHTA), CEIS, DEF, Faculty of Economics, University of Rome "Tor Vergata", Rome, Italy.
Andrea MarcellusiEconomic Evaluation and HTA (EEHTA), CEIS, DEF, Faculty of Economics, University of Rome "Tor Vergata", Rome, Italy.
Fausto BartoliniPharmaceutical Department, Local Health Unit Umbria 2, Terni, Italy.
Francesca Futura BernardiRegional Pharmaceutical Unit, Campania Region, 80143, Naples, Italy.
Fleur Levrat-GuillenAbbott Diabetes Care, Maidenhead, UK.
Marianna CozzolinoRegional Pharmaceutical Unit, Campania Region, 80143, Naples, Italy.
Massimo Di GennaroCampania Region Healthcare System Commissioner Office, Naples, Italy.
Roberta GiordanaCampania Region Healthcare System Commissioner Office, Naples, Italy.
Marianna GiustozziUmbria Digitale s.c.ar.l., Perugia, Italy.
Ugo TramaRegional Pharmaceutical Unit, Campania Region, 80143, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to define the distribution of direct healthcare costs for people with diabetes treated in two healthcare regions in Italy, based on number of comorbidities and treatment regimen.

methodsThis was a retrospective analysis using data from two local health authority administrative databases (Campania and Umbria) in Italy for the years 2014-2018. Data on hospital care, pharmaceutical and specialist outpatient and laboratory assistance were collected. All people with diabetes in 2014-2018 were identified on the basis of at least one prescription of hypoglycemic drugs (ATC A10), hospitalization with primary or secondary diagnosis of diabetes mellitus (ICD9CM 250.xx) or diabetes exemption code (code 013). Subjects were stratified into three groups according to their pharmaceutical prescriptions during the year: Type 1/type 2 diabetes (T1D/T2D) treated with multiple daily injections with insulin (MDI), type 2 diabetes on basal insulin only (T2D-Basal) and type 2 diabetes not on insulin therapy (T2D-Oral).

resultsWe identified 304,779 people with diabetes during the period for which data was obtained. Analysis was undertaken on 288,097 subjects treated with glucose-lowering drugs (13% T1D/T2D-MDI, 13% T2D-Basal, 74% T2D-Oral). Average annual cost per patient for the year 2018 across the total cohort was similar for people with T1D/T2D-MDI and people with T2D-Basal (respectively €2580 and €2254) and significantly lower for T2D-Oral (€1145). Cost of hospitalization was the main driver (47% for T1D/T2D-MDI, 45% for T2D-Basal, 45% for T2D-Oral) followed by drugs/devices (35%, 39%, 43%) and outpatient services (18%, 16%, 12%). Average costs increased considerably with increasing comorbidities: from €459 with diabetes only to €7464 for a patient with four comorbidities. Similar trends were found across all subgroups analysis.

conclusionAnnual cost of treatment for people with diabetes is similar for those treated with MDI or with basal insulin only, with hospitalization being the main cost driver. This indicates that both patient groups should benefit from having access to scanning continuous glucose monitoring (CGM) technology which is known to be associated with significantly reduced hospitalization for acute diabetes events, compared to self-monitored blood glucose (SMBG) testing.

Indexed as

Direct costsIntermittent continuous glucose monitoringItalyType 1 diabetesType 2 diabetes

Identifiers

PMID38668998
PMCPMC11096296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.