Evidence map›Paper›PMID 38668935›Full record

ArticleJournal of robotic surgery2024

Robotic-assisted hysterectomy for benign gynecologic disease in the United States: in-hospital use of opioid and non-opioid analgesics.

Simone Garzon, Andrea Mariani, Amy L Weaver, Michaela E Mcgree, Stefano Uccella, Fabio Ghezzi, Sean C Dowdy, Carrie L Langstraat, Gretchen E Glaser

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of robotic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Da VinciSurgical endoscopy · 2026
    Observational
  2. Article
  3. Review
  4. Article
  5. Opioid Use After Robotic Assisted versus Laparoscopic Endometriosis Surgery.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simone GarzonDepartment of Obstetrics and Gynecology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Andrea MarianiDepartment of Obstetrics and Gynecology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Amy L WeaverDepartment of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA.
Michaela E McgreeDepartment of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA.
Stefano UccellaUnit of Gynecology and Obstetrics, Department of Surgery, Dentistry, Pediatrics, and Gynecology, AOUI Verona, University of Verona, Verona, Italy.
Fabio GhezziDepartment of Obstetrics and Gynecology, "Filippo Del Ponte" Hospital, University of Insubria, Varese, Italy.
Sean C DowdyDepartment of Obstetrics and Gynecology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Carrie L LangstraatDepartment of Obstetrics and Gynecology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Gretchen E GlaserDepartment of Obstetrics and Gynecology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. glaser.gretchen@mayo.edu.

Funding

Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancerP50CA136393 · NCI · MAYO CLINIC ROCHESTER · PI ELLEN L. GOODE · 2009 to 2026
$37.0M
NCI NIH HHS P50 CA136393
6 · The paper itself

Abstract

To compare the in-hospital opioid and non-opioid analgesic use among women who underwent robotic-assisted hysterectomy (RH) vs. open (OH), vaginal (VH), or laparoscopic hysterectomy (LH). Records of women in the United States who underwent hysterectomy for benign gynecologic disease were extracted from the Premier Healthcare Database (2013-2019). Propensity score methods were used to create three 1:1 matched cohorts stratified in inpatients [RH vs. OH (N = 16,821 pairs), RH vs. VH (N = 6149), RH vs. LH (N = 11,250)] and outpatients [RH vs. OH (N = 3139), RH vs. VH (N = 29,954), RH vs. LH (N = 85,040)]. Opioid doses were converted to morphine milligram equivalents (MME). Within matched cohorts, opioid and non-opioid analgesic use was compared. On the day of surgery, the percentage of patients who received opioids differed only for outpatients who underwent RH vs. LH or VH (maximum difference = 1%; p < 0.001). RH was associated with lower total doses of opioids in all matched cohorts (each p < 0.001), with the largest difference observed between RH and OH: median (IQR) of 47.5 (25.0-90.0) vs. 82.5 (36.0-137.0) MME among inpatients and 39.3 (19.5-66.0) vs. 60.0 (35.0-113.3) among outpatients. After the day of surgery, fewer inpatients who underwent RH received opioids vs. OH (78.7 vs. 87.5%; p < 0.001) or LH (78.6 vs. 80.6%; p < 0.001). The median MME was lower for RH (15.0; 7.5-33.5) versus OH (22.5; 15.0-55.0; p < 0.001). Minor differences were observed for non-opioid analgesics. RH was associated with lower in-hospital opioid use than OH, whereas the same magnitude of difference was not observed for RH vs. LH or VH.

Indexed as

Analgesics, OpioidHysterectomyPostoperative PainRobotic Surgical ProceduresAdultAnalgesics, Non-NarcoticFemaleGenital Diseases, FemaleHumansLaparoscopyMiddle AgedPropensity ScoreUnited StatesAnalgesics, Non-NarcoticAnalgesics, OpioidAnalgesicsHysterectomyOpioidPremier healthcare databaseRobotic-assisted surgery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.