Evidence map›Paper›PMID 38668919›Full record

ArticleInfection2024

A case of pulmonary melioidosis in Germany: a rare differential diagnosis in returning travelers from South-East Asia.

Claudius Gottschalk, Marija Stojković, Sabine Zange, Peter Wolf, Julian A F Klein

Abstract readCase Reports
In one paragraph

Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Travel-Associated Melioidosis in Non-Endemic Regions: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2025
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudius GottschalkDepartment of Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0009-0004-3167-6123
Marija StojkovićDepartment of Infectious Diseases and Tropical Medicine, Centre for Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8721-9248
Sabine ZangeBundeswehr Institute of Microbiology, Munich, Germany.
Peter WolfDepartment of Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany.
Julian A F KleinDepartment of Virology, Centre for Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany. julian.klein@med.uni-heidelberg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMelioidosis is a bacterial infection associated with high mortality. The diagnostic approach to this rare disease in Europe is challenging, especially because pulmonary manifestation of melioidosis can mimic pulmonary tuberculosis (TB). Antibiotic therapy of melioidosis consists of an initial intensive phase of 2-8 weeks followed by an eradication therapy of 3-6 months. CASE PRESENTATION: We present the case of a 46-year-old female patient with pulmonary melioidosis in Germany. The patient showed chronic cough, a pulmonary mass and a cavitary lesion, which led to the initial suspicion of pulmonary TB. Melioidosis was considered due to a long-term stay in Thailand with recurrent exposure to rice fields.

resultsMicrobiologic results were negative for TB. Histopathology of an endobronchial tumor showed marked chronic granulation tissue and fibrinous inflammation. Melioidosis was diagnosed via polymerase chain reaction by detection of Burkholderia pseudomallei/mallei target from mediastinal lymph-node tissue.

conclusionThis case report emphasizes that melioidosis is an important differential diagnosis in patients with suspected pulmonary tuberculosis and recent travel to South-East Asia.

Indexed as

Burkholderia pseudomalleiMelioidosisAnti-Bacterial AgentsAsia, SoutheasternDiagnosis, DifferentialFemaleGermanyHumansMiddle AgedThailandTravelTuberculosis, PulmonaryAnti-Bacterial AgentsBurkholderia pseudomalleiCase reportCavitary lung lesionPulmonary melioidosis

Identifiers

PMID38668919
PMCPMC11499404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.