Evidence map›Paper›PMID 38668914›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2024

The Profile and Content of Polyphenolic Compounds and Antioxidant and Anti-Glycation Properties of Root Extracts of Selected Medicinal Herbs.

Patrycja Chociej, Kamil Foss, Monika Jabłońska, Małgorzata Ustarbowska, Tomasz Sawicki

Abstract read
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Antioxidants (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Raisin as a Functional Food: Antioxidant and Antiglycation Activity Assessed by Model Systems.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrycja ChociejDepartment of Human Nutrition, Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Słoneczna 45F, Olsztyn, 10-719, Poland.ORCID http://orcid.org/0009-0005-1968-2122
Kamil FossDepartment of Human Nutrition, Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Słoneczna 45F, Olsztyn, 10-719, Poland.ORCID http://orcid.org/0000-0002-4931-1374
Monika JabłońskaDepartment of Human Nutrition, Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Słoneczna 45F, Olsztyn, 10-719, Poland. monika.jablonska@uwm.edu.pl.ORCID http://orcid.org/0000-0002-7554-6433
Małgorzata UstarbowskaA. Chetnika Vocantional School, Complex No 4, Traugutta 10, Ostrołęka, 07-410, Poland.
Tomasz SawickiDepartment of Human Nutrition, Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Słoneczna 45F, Olsztyn, 10-719, Poland. tomasz.sawicki@uwm.edu.pl.ORCID http://orcid.org/0000-0002-4304-1625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of our study was to analyse the extracts from six medicinal herb roots (marshmallow, dandelion, liquorice, angelica, burdock, and comfrey) in terms of antioxidant capacity (ABTS, DPPH) and inhibition of advanced glycation end product (AGEs) formation. The quantification of phenolic acids and flavonoids was analysed using the UHPLC-DAD-MS method. Fifteen polyphenolic compounds were detected in the studied herbs. The higher number of polyphenols were found in marshmallows (ten polyphenols), while the lowest was in comfrey (five compounds). Liquorice root revealed the highest individual phenolic concentration (382 µg/g dm) with the higher contribution of kaempferol-3-O-rutinoside. Comfrey root extract was characterised by the most abundant TPC (Total Phenolic Content) value (29.79 mg GAE/ g dm). Burdock and comfrey showed the strongest anti-AGE activity studies with the BDA-GLU model. Burdock root was also characterised by the highest anti-AGE activity in the BSA-MGO model. The highest antioxidant capacity was determined by ABTS (72.12 µmol TE/g dw) and DPPH (143.01 µmol TE/g dw) assays for comfrey extract. The p-coumaric acid content was significantly correlated with anti-AGE activity determined by the BSA-MGO model. This research sheds new light on the bioactivity of root herbs, explaining the role of p-coumaric acid in preventing diabetes.

Indexed as

AntioxidantsFlavonoidsGlycation End Products, AdvancedPlant ExtractsPlant RootsPlants, MedicinalPolyphenolsAngelicaArctiumChromatography, High Pressure LiquidCoumaric AcidsGlycyrrhizaHydroxybenzoatesPropionatesAntioxidantsCoumaric AcidsFlavonoidsGlycation End Products, AdvancedHydroxybenzoatesp-coumaric acidphenolic acidPlant ExtractsPolyphenolsPropionatesAGEs inhibitionAntioxidant activityFlavonoidsHerbsPhenolic acids

Identifiers

PMID38668914
PMCPMC11178571

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.