Evidence map›Paper›PMID 38668874›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2024

NovoSorb® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children.

Safiullah Najem, Miriam Fattouh, Kristofer Wintges, Benjamin Schoof, Merle Koerner, Konrad Reinshagen, Ingo Koenigs

Abstract read
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. NovosorbFrontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Safiullah NajemDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany.
Miriam FattouhDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany.
Kristofer WintgesDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany.
Benjamin SchoofDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany.
Merle KoernerDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany.
Konrad ReinshagenDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany.
Ingo KoenigsDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20251, Hamburg, Germany. ingo.koenigs@uke.de.ORCID http://orcid.org/0000-0002-1986-4066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn pediatric population, large soft tissue defects occur in avulsion injuries. In addition to the challenges of primary surgical therapy, elasticity, appearance and function of the scar in children are of crucial importance, especially in the context of body growth. So far various flaps, plasties, skin grafts and dermal substitutes have become established, although infections and skin shrinkage remain challenging. In 2020, a new skin substitute material-NovoSorb® Biodegradable Temporizing Matrix (BTM)-was introduced in Europe for temporary wound closure and tissue regeneration. The aim of this study was to evaluate the value of BTM in pediatric patients.

methodsThe study included all children treated with BTM after traumatic soft tissue defects following limb avulsion injuries between June 2021 and June 2023 at a university hospital.

results7 patients with limb avulsion injuries were treated with BTM, 4 boys, 3 girls. Mean age was 6.5 years (2-11 years) at the time of BTM placement. 4/7 had concomitant fractures. BTM was used successfully in all cases, infection did not occur, skin shrinkage was seen in one case. Split thickness skin graft (STSG) after BTM application was performed in average after 33 days (26 to 39 days). Limitations of this study were highlighted.

conclusionBTM is a promising alternative for reconstruction of complex trauma extremity wounds in children following avulsion injuries, even in cases of concomitant bone injuries. Interpretation may be limited by sample size.

Indexed as

Skin TransplantationSoft Tissue InjuriesAbsorbable ImplantsChildChild, PreschoolFemaleHumansMalePlastic Surgery ProceduresRetrospective StudiesSkin, ArtificialAvulsion injuryBTMDermal skin substitutesPediatricTemplatesWound therapy

Identifiers

PMID38668874
PMCPMC11458696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.