Evidence map›Paper›PMID 38668845›Full record

ArticleApplied biochemistry and biotechnology2024

Human Umbilical Cord-Derived Mesenchymal Stem Cells-Exosomes-Delivered miR-375 Targets HDAC4 to Promote Autophagy and Suppress T Cell Apoptosis in Sepsis-Associated Acute Kidney Injury.

Min Liu, Xiyun Chen

Abstract read
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In one paragraph

Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Min LiuDepartment of Intensive Care, the First Hospital of Changsha, No. 311 Yingpan Road, Changsha, Hunan, 410005, People's Republic of China.
Xiyun ChenDepartment of Gynecology, the First Hospital of Changsha, No. 311 Yingpan Road, Changsha, Hunan, 410005, People's Republic of China. x123465732@163.com.ORCID http://orcid.org/0009-0005-0633-1980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study sought to elucidate the mechanism of human umbilical cord-derived mesenchymal stem cells (HUCMSCs)-exosomes (Exos) in sepsis-associated acute kidney injury (SAKI). Exos were isolated from HUCMSCs and co-cultured with CD4

Indexed as

Acute Kidney InjuryApoptosisAutophagyExosomesHistone DeacetylasesMesenchymal Stem CellsMicroRNAsSepsisUmbilical CordAnimalsCD4-Positive T-LymphocytesHumansMaleMiceRepressor ProteinsHDAC4 protein, humanHistone DeacetylasesMicroRNAsMIRN375 microRNA, humanRepressor ProteinsApoptosisAutophagyCD4+ TExosomesHDAC4HUCMSCsmiR-375Sepsis-associated acute kidney injury

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.