Sortase-Modified Cholera Toxoids Show Specific Golgi Localization.
Darren C Machin, Daniel J Williamson, Peter Fisher, Victoria J Miller, Zoe L P Arnott, Charlotte M E Stevenson, Gemma C Wildsmith, James F Ross, Christopher W Wasson, Andrew Macdonald and 4 more
Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors at 4 institutions in 1 country.
Darren C MachinSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-7954-8017
Daniel J WilliamsonSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Peter FisherDepartment of Biology, University of York, York YO10 5DD, UK.
Victoria J MillerDepartment of Biochemistry, University of Bristol, Bristol BS8 1QU, UK.
Zoe L P ArnottSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Charlotte M E StevensonSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Gemma C WildsmithSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
James F RossSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0002-4784-103X
Christopher W WassonFaculty of Biological Sciences, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Andrew MacdonaldFaculty of Biological Sciences, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0002-5978-4693
Benjamin I AndrewsGlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, UK.ORCID 0000-0002-7852-3675
W Bruce TurnbullSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0002-7352-0360
Michael E WebbSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
University of Leeds · GBUniversity of York · GBGlaxoSmithKline (United Kingdom) · GBUniversity of Bristol · GB
Funding
Biotechnology and Biological Sciences Research Council BB/J014443/1Biotechnology and Biological Sciences Research Council BB/K501049/1Biotechnology and Biological Sciences Research Council BB/M005666/1Biotechnology and Biological Sciences Research Council BB/M011151/1Biotechnology and Biological Sciences Research Council BB/P028152/1Biotechnology and Biological Sciences Research Council BB/R005540/1Biotechnology and Biological Sciences Research Council BB/W01131X/1Medical Research Council MR/J000604/1Medical Research Council MR/K012665Medical Research Council MR/S001697/1Wellcome TrustWellcome Trust 089308/Z/09/Z
6 · The paper itself
Abstract
Cholera toxoid is an established tool for use in cellular tracing in neuroscience and cell biology. We use a sortase labeling approach to generate site-specific N-terminally modified variants of both the A2-B
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Sortase-Modified Cholera Toxoids Show Specific Golgi Localization. · full record | OpenQuestion