Evidence map›Paper›PMID 38668613›Full record

ArticleToxins2024

Effect of Seaweed-Derived Fucoidans from

Camila Castro-Pinheiro, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Ana Cláudia Rodrigues da Silva, Corinna A Dwan, Samuel S Karpiniec, Alan Trevor Critchley, Andre Lopes Fuly

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Role ofMarine drugs · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Camila Castro-PinheiroDepartment of Molecular and Cellular Biology, Federal Fluminense University, Niterói 24001-970, Rio de Janeiro, Brazil.ORCID 0000-0001-8282-529X
Luiz Carlos Simas Pereira JuniorDepartment of Molecular and Cellular Biology, Federal Fluminense University, Niterói 24001-970, Rio de Janeiro, Brazil.
Eladio Flores SanchezLaboratory of Biochemistry of Proteins from Animal Venoms, Research and Development Center, Ezequiel Dias Foundation, Belo Horizonte 30510-010, Minas Gerais, Brazil.
Ana Cláudia Rodrigues da SilvaDepartment of Molecular and Cellular Biology, Federal Fluminense University, Niterói 24001-970, Rio de Janeiro, Brazil.
Corinna A DwanMarinova Pty, Ltd., Cambridge, TAS 7170, Australia.ORCID 0000-0001-8437-0743
Samuel S KarpiniecMarinova Pty, Ltd., Cambridge, TAS 7170, Australia.ORCID 0009-0006-4225-8626
Alan Trevor CritchleyIndependent Researcher, The Evangeline Trail, Highway 1, Paradise, NS B0S 1R0, Canada.ORCID 0000-0003-1704-458X
Andre Lopes FulyDepartment of Molecular and Cellular Biology, Federal Fluminense University, Niterói 24001-970, Rio de Janeiro, Brazil.ORCID 0000-0002-5265-5258
Universidade Federal Fluminense · BREzequiel Dias Foundation · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304719/2012-9Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.163/2014 and E-26/01.001918/2015Fundação de Amparo à Pesquisa do Estado de Minas Gerais AUC-00022-16, APQ-01858-15International Foundation for Science F/457-1
6 · The paper itself

Abstract

backgroundSnakebite envenomation (SBE) causes diverse toxic effects in humans, including disability and death. Current antivenom therapies effectively prevent death but fail to block local tissue damage, leading to an increase in the severity of envenomation; thus, seeking alternative treatments is crucial.

methodsThis study analyzed the potential of two fucoidan sulfated polysaccharides extracted from brown seaweeds

resultsFVF and UPF did not lyse human red blood cells. FVF and UPF inhibited the proteolytic activity of

conclusionFVF and UPF may be of importance as adjuvants for SBE caused by species of

Indexed as

Blood CoagulationCrotalid VenomsFucusPhospholipases A2PolysaccharidesUndariaAnimalsAntiveninsBothropsBothrops jararacaEdible SeaweedsProteolysisSeaweedVenomous SnakesAntiveninsCrotalid VenomsfucoidanPhospholipases A2PolysaccharidesantivenomBothropsbrown seaweedfucoidanFucus vesiculosussnake venomUndaria pinnatifida

Identifiers

PMID38668613
PMCPMC11053494
OpenAlexW4394753812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.