ReviewToxins2024
The Role of Botulinum Toxin Type-A in Spasticity: Research Trends from a Bibliometric Analysis.
Review in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Botulinum Toxin Combined with Robot-Assisted Therapy for Post-Stroke Spasticity: A Systematic Review.Toxins · 2025Pooled it
- Current Strategies in the Development of Nanoformulations to Enhance the Stability of Botox: A Systematic Review.AAPS PharmSciTech · 2025Pooled it
- Acupuncture therapy for post-stroke spasticity: a systematic review and exploratory network meta-analysis of clinical efficacy and dose-response relationship.Frontiers in neurologyPooled it
- Home-based modified constraint-induced movement therapy improves distal motor outcomes after botulinum toxin A injection in chronic stroke.Frontiers in neurology · 2026Trial
- Ultrasound-Guided Alcohol Neurolysis for Poststroke Upper Limb Spasticity to Facilitate Arteriovenous Fistula Creation in Hemodialysis: A Case Report.Archives of rehabilitation research and clinical translation · 2026Article
- Adverse neurological events following botulinum toxin type A: A case series of post-injection seizures and paralysis.Toxicon: X · 2026Article
- Muscle-Specific Dosing of OnabotulinumtoxinA in Post-Stroke Upper-Limb Spasticity: A Descriptive Literature Review.Toxins · 2026Review
- Botulinum toxin A for post-stroke spasticity: Insights from the French National Hospital Discharge Database (2015-2023).European stroke journal · 2026Article
- Research progress in the use of botulinum toxin type a for post-stroke spasticity rehabilitation: a narrative review.Annals of medicine · 2025Review
- Botulinum toxin A for post-stroke spasticity: Insights from the French National Hospital Discharge Database (2015-2023).European stroke journal · 2025Article
- Botulinum toxin type A for amyotrophic lateral sclerosis lower limb spasm: two case reports.BMC neurology · 2025Article
- Ultrasound-Guided Botulinum Toxin Injections for Hand Spasticity: A Technical Guide for the Dorsal Approach.Toxins · 2025Article
- Observational
- Pioneering pain management with botulinum toxin type A: From anti-inflammation to regenerative therapies.Heliyon · 2025Review
- Review
- Review
- Stroke rehabilitation: from diagnosis to therapy.Frontiers in neurology · 2024Review
- Efficacy and safety of acupuncture for post-stroke spasticity: a study protocol for a randomized controlled trial.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Botulinum toxin type-A (BoNT-A) has emerged as a key therapeutic agent for the management of spasticity. This paper presents a comprehensive bibliometric and visual analysis of research concerning BoNT-A treatment of spasticity to elucidate current trends and future directions in this research area. A search was conducted in the Web of Science database for articles focused on the use of BoNT-A in spasticity published between 2000 and 2022. We extracted various metrics, including counts of publications and contributions from different countries, institutions, authors, and journals. Analytical methods in CiteSpace were employed for the examination of co-citations, collaborations, and the co-occurrence of keywords. Our search yielded 1489 publications. Analysis revealed a consistent annual increase in research output. The United States, United Kingdom, and Italy were the leading contributors. The top institution in this research was Assistance Publique Hopitaux, Paris. The journal containing the highest number of relevant publications was
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.