Evidence map›Paper›PMID 38668593›Full record

ArticleToxins2024

Effects of a Curcumin/Silymarin/Yeast-Based Mycotoxin Detoxifier on Redox Status and Growth Performance of Weaned Piglets under Field Conditions.

Vasileios G Papatsiros, Georgios I Papakonstantinou, Nikolaos Voulgarakis, Christos Eliopoulos, Christina Marouda, Eleftherios Meletis, Irene Valasi, Polychronis Kostoulas, Dimitrios Arapoglou, Insaf Riahi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Vasileios G PapatsirosClinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0003-4955-0460
Georgios I PapakonstantinouClinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0002-3434-0877
Nikolaos VoulgarakisClinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0001-5567-1328
Christos EliopoulosInstitute of Technology of Agricultural Products, Hellenic Agricultural Organization-Demeter (HAO-Demeter), 14123 Athens, Greece.ORCID 0000-0003-0702-3718
Christina MaroudaLaboratory of Pathology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-1637-2517
Eleftherios MeletisLaboratory of Epidemiology & Artificial Intelligence, Faculty of Public Health, School of Health Sciences, University of Thessaly, Terma Mavromichali St., 43100 Karditsa, Greece.ORCID 0000-0003-2862-7182
Irene ValasiLaboratory of Physiology, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece.
Polychronis KostoulasLaboratory of Epidemiology & Artificial Intelligence, Faculty of Public Health, School of Health Sciences, University of Thessaly, Terma Mavromichali St., 43100 Karditsa, Greece.ORCID 0000-0001-7051-1541
Dimitrios ArapoglouInstitute of Technology of Agricultural Products, Hellenic Agricultural Organization-Demeter (HAO-Demeter), 14123 Athens, Greece.ORCID 0000-0002-6526-5945
Insaf RiahiBiōnte Animal Nutrition, 43100 Reus, Spain.
Georgios ChristodoulopoulosDepartment of Animal Science, Agricultural University of Athens, 75 Iera Odos Street, Votanikos, 11855 Athens, Greece.ORCID 0000-0002-2692-8910
Dimitra PsallaLaboratory of Pathology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-1539-4124
University of Thessaly · GRAristotle University of Thessaloniki · GRAgricultural University of Athens · GR

Funding

Biōnte Nutrition S.L. (Reus-Tarragona, Spain) 7343
6 · The paper itself

Abstract

The aim of this in vivo study was to investigate the effects of a novel mycotoxin detoxifier whose formulation includes clay (bentonite and sepiolite), phytogenic feed additives (curcumin and silymarin) and postbiotics (yeast products) on the health, performance and redox status of weaned piglets under the dietary challenge of fumonisins (FUMs). The study was conducted in duplicate in the course of two independent trials on two different farms. One hundred and fifty (150) weaned piglets per trial farm were allocated into two separate groups: (a) T1 (control group): 75 weaned piglets received FUM-contaminated feed and (b) T2 (experimental group): 75 weaned piglets received FUM-contaminated feed with the mycotoxin-detoxifying agent from the day of weaning (28 days) until 70 days of age. Thiobarbituric acid reactive substances (TBARSs), protein carbonyls (CARBs) and the overall antioxidant capacity (TAC) were assessed in plasma as indicators of redox status at 45 and 70 days of age. Furthermore, mortality and performance parameters were recorded at 28, 45 and 70 days of age, while histopathological examination was performed at the end of the trial period (day 70). The results of the present study reveal the beneficial effects of supplementing a novel mycotoxin detoxifier in the diets of weaners, including improved redox status, potential hepatoprotective properties and enhanced growth performance.

Indexed as

Animal FeedCurcuminOxidation-ReductionWeaningAluminum SilicatesAnimalsAntioxidantsBentoniteFood ContaminationFumonisinsLiverMaleMycotoxinsProtein CarbonylationSwineThiobarbituric Acid Reactive SubstancesAluminum SilicatesAntioxidantsBentoniteCurcuminFumonisinsMycotoxinssodium calcium aluminosilicate, hydratedThiobarbituric Acid Reactive SubstancesCARBscurcumindetoxifierfumonisinsmycotoxinpigsilymarinTACTBARSyeast

Identifiers

PMID38668593
PMCPMC11054618
OpenAlexW4393163945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.