Evidence map›Paper›PMID 38668580›Full record

ArticleSports (Basel, Switzerland)2024

Impact of Isolated Exercise-Induced Small Airway Dysfunction on Exercise Performance in Professional Male Cyclists.

Konstantinos M Pigakis, Vasileios T Stavrou, Aggeliki K Kontopodi, Ioannis Pantazopoulos, Zoe Daniil, Konstantinos Gourgoulianis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sports (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Konstantinos M PigakisDepartment of Respiratory & Critical Care Medicine, Creta Interclinic, 71304 Heraklion, Greece.ORCID 0000-0001-9131-2939
Vasileios T StavrouLaboratory of Cardiopulmonary Testing and Pulmonary Rehabilitation, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0002-2437-5339
Aggeliki K KontopodiDepartment of Respiratory & Critical Care Medicine, Creta Interclinic, 71304 Heraklion, Greece.
Ioannis PantazopoulosDepartment of Emergency Medicine, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0002-8846-519X
Zoe DaniilLaboratory of Cardiopulmonary Testing and Pulmonary Rehabilitation, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Konstantinos GourgoulianisLaboratory of Cardiopulmonary Testing and Pulmonary Rehabilitation, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0001-9541-1010
University of Thessaly · GRPolyclinic General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProfessional cycling puts significant demands on the respiratory system. Exercise-induced bronchoconstriction (EIB) is a common problem in professional athletes. Small airways may be affected in isolation or in combination with a reduction in forced expiratory volume at the first second (FEV MATERIALS AND

methodsThis research was conducted on professional cyclists with no history of asthma or atopy. Anthropometric characteristics were recorded, the training age was determined, and spirometry and specific markers, such as fractional exhaled nitric oxide (FeNO) and immunoglobulin E (IgE), were measured for all participants. All of the cyclists underwent cardiopulmonary exercise testing (CPET) followed by spirometry.

resultsCompared with the controls, 1-FEV

conclusionsAccording to our data, it appears that professional cyclists may experience no beneficial impacts on their respiratory system. Strenuous endurance exercise can induce airway injury, which is followed by a restorative process. The repeated cycle of injury and repair can trigger the release of pro-inflammatory mediators, the disruption of the airway epithelial barrier, and plasma exudation, which gradually give rise to airway hyper-responsiveness, exercise-induced bronchoconstriction, intrabronchial inflammation, peribronchial fibrosis, and respiratory symptoms. The small airways may be affected in isolation or in combination with a reduction in FEV

Indexed as

cardiopulmonary exercise testingexercise-induced airway injuryexercise-induced bronchoconstrictionisolated exercise-induced small airway dysfunctionpulmonary function testssmall airway diseasespirometry

Identifiers

PMID38668580
PMCPMC11054898
OpenAlexW4394954796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.