Evidence map›Paper›PMID 38668512›Full record

ArticleToxics2024

Urinary Volatile Organic Compound Metabolites Are Associated with Reduced Lung Function in U.S. Children and Adolescents.

Angelico Mendy, Sara Burcham, Ashley L Merianos, Tesfaye B Mersha, Kimberly Yolton, Aimin Chen, E Melinda Mahabee-Gittens

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Angelico MendyDivision of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
Sara BurchamDivision of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.ORCID 0000-0002-0976-8425
Ashley L MerianosSchool of Human Services, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0002-5640-7227
Tesfaye B MershaDivision of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.ORCID 0000-0002-9189-8447
Kimberly YoltonGeneral and Community Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.ORCID 0000-0002-4458-0516
Aimin ChenDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
E Melinda Mahabee-GittensDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.ORCID 0000-0002-3893-885X
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati Medical Center · USUniversity of Cincinnati · USUniversity of Pennsylvania · US

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
Unraveling ancestry and environmental exposure interactions in childhood asthmaR01HL132344 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2016 to 2020
$3.4M
Epigenome-wide variations and socio-environmental exposures in African American asthmatic childrenR01HG011411 · NHGRI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2021 to 2025
$3.4M
Supplement: Contribution of Thirdhand Smoke to Overall Tobacco SmokeR01ES027815 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI MAHABEE-GITTENS, E. MELINDA, MATT, GEORG E · 2018 to 2022
$3.1M
Childhood and In utero Exposure to Organophosphate and Replacement Brominated Flame Retardants and Child Respiratory OutcomesR01ES034049 · NIEHS · UNIVERSITY OF CINCINNATI · PI MENDY, ANGELICO · 2022 to 2024
$874k
Reducing Secondhand Smoke Exposure Among Pediatric Patients in the Emergency Department SettingK01DA044313 · NIDA · UNIVERSITY OF CINCINNATI · PI MERIANOS, ASHLEY L · 2017 to 2021
$727k
Distinguishing Exposure to Secondhand and Thirdhand Tobacco Smoke and Electronic Cigarettes among U.S. Children based on Multiple Biomarker ProfilesR21ES032161 · NIEHS · UNIVERSITY OF CINCINNATI · PI MERIANOS, ASHLEY L · 2020 to 2021
$467k
NHGRI NIH HHS R01 HG011411NHGRI NIH HHS R01HG011411NHLBI NIH HHS R01 HL132344NIDA NIH HHS K01 DA044313NIDA NIH HHS K01DA044313NIEHS NIH HHS P30 ES006096NIEHS NIH HHS R01 ES027815NIEHS NIH HHS R01 ES034049NIEHS NIH HHS R01ES034049, P30ES006096, R21ES032161, R01ES03743, R01ES027815NIEHS NIH HHS R21 ES032161
6 · The paper itself

Abstract

(1) Background: Volatile organic compounds (VOCs) are indoor pollutants absorbed by inhalation. The association of several VOCs with lung function in children and adolescents is unknown. (2) Methods: We analyzed 505 participants, 6-17-year-olds from the 2011-2012 National Health and Nutrition Examination Survey. Multiple linear regression models were fitted to estimate the associations of VOC metabolites with spirometry outcomes adjusting for covariates. (3) Results: Urinary metabolites of xylene, acrylamide, acrolein, 1,3-butadiene, cyanide, toluene, 1-bromopropane, acrylonitrile, propylene oxide, styrene, ethylbenzene, and crotonaldehyde were all detected in ≥64.5% of participants. Forced expiratory volume in 1 s (FEV

Indexed as

children respiratory healthenvironmental exposuresurinary metabolitesvolatile organic compounds

Identifiers

PMID38668512
PMCPMC11054577
OpenAlexW4394843799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.