Evidence map›Paper›PMID 38668297›Full record

ArticlePathogens (Basel, Switzerland)2024

Antimicrobial Activity of Methylene Blue Associated with Photodynamic Therapy: In Vitro Study in Multi-Species Oral Biofilm.

Bruno Bueno-Silva, Javier Parma-Garcia, Lucio Frigo, Lina J Suárez, Tatiane Tiemi Macedo, Fábio Hideaki Uyeda, Marcelo Augusto Ruiz da Cunha Melo, Roberto Sacco, Carlos Fernando Mourão, Magda Feres and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Bruno Bueno-SilvaDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.ORCID 0000-0003-3275-5910
Javier Parma-GarciaDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.
Lucio FrigoDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.ORCID 0000-0001-9131-1071
Lina J SuárezDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.
Tatiane Tiemi MacedoDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.
Fábio Hideaki UyedaDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.
Marcelo Augusto Ruiz da Cunha MeloDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.ORCID 0000-0002-6398-5703
Roberto SaccoDepartment of Oral Surgery, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9SP, UK.ORCID 0000-0002-8413-1053
Carlos Fernando MourãoDepartment of Periodontology, Dental Research Division, Tuft University School of Dental Medicine, Boston, MA 02111, USA.ORCID 0000-0001-5775-0222
Magda FeresDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.
Jamil Awad ShibliDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.ORCID 0000-0003-1971-0195
Luciene Cristina FigueiredoDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.
Guarulhos University · BRHarvard University · USKing's College London · GBTufts University · USUniversidade Estadual de Campinas (UNICAMP) · BRUniversidad Nacional de Colombia · CO

Funding

Coordination for the Improvement of Higher Education Personel, #001 CAPESNational Council for Scientific and Technological Development # 311368/2019-0 CNPq
6 · The paper itself

Abstract

The control of infectious diseases caused by biofilms is a continuing challenge for researchers due to the complexity of their microbial structures and therapeutic implications. Photodynamic therapy as an adjunctive anti-infective treatment has been described as a possible valid approach but has not been tested in polymicrobial biofilm models. This study evaluated the effect of photodynamic therapy in vitro with methylene blue (MB) 0.01% and red LEDs (λ = 660 nm, power density ≈ 330 mW/cm

Indexed as

BiofilmsMethylene BluePhotochemotherapyAnti-Infective AgentsBacteriaHumansMouthPhotosensitizing AgentsAnti-Infective AgentsMethylene BluePhotosensitizing Agentsbiofilmslasermethylene blueperi-implantitisperiodontal diseasesphotodynamic therapy

Identifiers

PMID38668297
PMCPMC11054395
OpenAlexW4395001072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.