Evidence map›Paper›PMID 38668263›Full record

ArticlePathogens (Basel, Switzerland)2024

Pregnancy Management in HIV Viral Controllers: Twenty Years of Experience.

Charlotte-Eve S Short, Laura Byrne, Aishah Hagan-Bezgin, Rachael A Quinlan, Jane Anderson, Gary Brook, Okavas De Alwis, Annemiek de Ruiter, Pippa Farrugia, Sarah Fidler and 15 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. The elite controller phenotype.Current opinion in HIV and AIDS · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 11 institutions in 1 country.

Charlotte-Eve S ShortDepartment of Infectious Disease, Imperial College London, London W2 1PG, UK.
Laura ByrneSchool of Medicine, St Georges, University of London, London SW17 0RE, UK.
Aishah Hagan-BezginDepartment of Infectious Disease, Imperial College London, London W2 1PG, UK.
Rachael A QuinlanDepartment of Infectious Disease, Imperial College London, London W2 1PG, UK.ORCID 0000-0001-6074-0607
Jane AndersonHomerton Healthcare NHS Foundation Trust, London E9 6SR, UK.
Gary BrookLondon North West University Healthcare NHS Trust, Harrow HA1 3UJ, UK.
Okavas De AlwisImperial College Healthcare NHS Trust, London W2 1NY, UK.
Annemiek de RuiterGuy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Pippa FarrugiaGuy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Sarah FidlerDepartment of Infectious Disease, Imperial College London, London W2 1PG, UK.
Eleanor HamlynRoyal Free London NHS Foundation Trust, London NW3 2QG, UK.
Anna HartleyBarts Health NHS Trust, London E1 1BB, UK.
Siobhan MurphyLondon North West University Healthcare NHS Trust, Harrow HA1 3UJ, UK.
Heather NobleBarts Health NHS Trust, London E1 1BB, UK.
Soonita OomeerImperial College Healthcare NHS Trust, London W2 1NY, UK.ORCID 0009-0000-4558-4036
Sherie RoedlingCentral and North West London NHS Foundation Trust, London NW1 3AX, UK.
Melanie RosenvingeLewisham and Greenwich NHS Trust, London SE13 6LH, UK.
Luciana RubinsteinLondon North West University Healthcare NHS Trust, Harrow HA1 3UJ, UK.ORCID 0009-0001-1614-125X
Rimi ShahRoyal Free London NHS Foundation Trust, London NW3 2QG, UK.
Selena SinghBarts Health NHS Trust, London E1 1BB, UK.
Elizabeth ThorneDepartment of Infectious Disease, Imperial College London, London W2 1PG, UK.
Martina TobyBarts Health NHS Trust, London E1 1BB, UK.
Brenton WaitHomerton Healthcare NHS Foundation Trust, London E9 6SR, UK.
Liat SarnerBarts Health NHS Trust, London E1 1BB, UK.
Graham P TaylorDepartment of Infectious Disease, Imperial College London, London W2 1PG, UK.ORCID 0000-0002-3773-2390
Imperial College Healthcare NHS Trust · GBBarts Health NHS Trust · GBLondon North West Healthcare NHS Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBCentral and North West London NHS Foundation Trust · GBHomerton University Hospital NHS Foundation Trust · GBLewisham and Greenwich NHS Trust · GBNIHR Imperial Biomedical Research Centre · GBSt George's, University of London · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The evidence base for the management of spontaneous viral controllers in pregnancy is lacking. We describe the management outcomes of pregnancies in a series of UK women with spontaneous HIV viral control (<100 copies/mL 2 occasions before or after pregnancy off ART). (2) Methods: A multi-centre, retrospective case series (1999-2021) comparing pre- and post-2012 when guidelines departed from zidovudine-monotherapy (ZDVm) as a first-line option. Demographic, virologic, obstetric and neonatal information were anonymised, collated and analysed in SPSS. (3) Results: A total of 49 live births were recorded in 29 women, 35 pre-2012 and 14 post. HIV infection was more commonly diagnosed in first reported pregnancy pre-2012 (15/35) compared to post (2/14),

Indexed as

Anti-HIV AgentsHIV InfectionsInfectious Disease Transmission, VerticalPregnancy Complications, InfectiousAdultFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeRetrospective StudiesUnited KingdomViral LoadYoung AdultZidovudineAnti-HIV AgentsZidovudineantiretroviral therapyelite HIV viral controllerHIV-1 vertical transmissionobstetric managementpregnancy

Identifiers

PMID38668263
PMCPMC11054990
OpenAlexW4394692046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.