Evidence map›Paper›PMID 38668256›Full record

ArticlePathogens (Basel, Switzerland)2024

Pentavalent Antimony Associated with G-CSF in the Treatment of Cutaneous Leishmaniasis Caused by

Carvel Suprien, Luiz H Guimarães, Lucas P de Carvalho, Paulo R L Machado

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Carvel SuprienPostgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Bahia, Salvador 40026-010, Bahia, Brazil.ORCID 0000-0003-1046-0476
Luiz H GuimarãesNational Institutes of Science and Technology in Tropical Diseases, Ministry of Science and Technology, Salvador, Bahia, Brazil.
Lucas P de CarvalhoPostgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Bahia, Salvador 40026-010, Bahia, Brazil.
Paulo R L MachadoPostgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Bahia, Salvador 40026-010, Bahia, Brazil.ORCID 0000-0003-1894-6171
Universidade Federal da Bahia · BRUniversidade Federal do Recôncavo da Bahia · BR

Funding

Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais 465229/2014-0
6 · The paper itself

Abstract

Cutaneous leishmaniasis (CL), caused by

methodsThis study compares the effectiveness of G-CSF associated with MA in the treatment of CL. A total of 32 patients aged between 18 and 50 years with CL confirmed for

resultsMales predominated in the G-CSF group (59%), while females predominated in the control group (53%). Injuries to the lower limbs predominated in both study groups. The cure rate in the G-CSF group was 65% and in the control group it was 47%, 90 days after initiation of therapy.

conclusionsOur data indicate that the association of G-CSF with MA is not superior to MA monotherapy. Although not significant, the potential benefit of this combination deserves further investigation. The use of higher doses or other routes of application of G-CSF in a greater number of patients should contribute to a definitive response.

Indexed as

Antiprotozoal AgentsGranulocyte Colony-Stimulating FactorLeishmania braziliensisLeishmaniasis, CutaneousAdolescentAdultAntimonyDrug Therapy, CombinationFemaleHumansMaleMeglumineMeglumine AntimoniateMiddle AgedOrganometallic CompoundsTreatment OutcomeAntimonyAntiprotozoal AgentsGranulocyte Colony-Stimulating FactorMeglumineMeglumine AntimoniateOrganometallic CompoundsCutaneous leishmaniasisgranulocyte colony stimulating factorLeishmania Viannia braziliensismeglumine antimoniatetreatment

Identifiers

PMID38668256
PMCPMC11054058
OpenAlexW4393949356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.