Evidence map›Paper›PMID 38668244›Full record

ArticlePathogens (Basel, Switzerland)2024

Measurement of Feline Alpha-1 Acid Glycoprotein in Serum and Effusion Using an ELISA Method: Analytical Validation and Diagnostic Role for Feline Infectious Peritonitis.

Pierpaolo Romanelli, Walter Bertazzolo, Andrea Prisciandaro, Andrea Leone, Ugo Bonfanti, Saverio Paltrinieri

Open access · goldAbstract readValidation Study
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pierpaolo RomanelliMYLAV Veterinary Laboratory, 20017 Passirana di Rho, Italy.ORCID 0000-0001-7310-0641
Walter BertazzoloMYLAV Veterinary Laboratory, 20017 Passirana di Rho, Italy.
Andrea PrisciandaroMYLAV Veterinary Laboratory, 20017 Passirana di Rho, Italy.
Andrea LeoneMYLAV Veterinary Laboratory, 20017 Passirana di Rho, Italy.
Ugo BonfantiMYLAV Veterinary Laboratory, 20017 Passirana di Rho, Italy.
Saverio PaltrinieriDepartment of Veterinary Medicine and Animal Sciences, University of Milan, 26900 Lodi, Italy.ORCID 0000-0001-7117-7987
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlpha-1 acid glycoprotein (AGP) may support a clinical diagnosis of feline infectious peritonitis (FIP). In this study, we assessed the analytical and diagnostic performances of a novel ELISA method to measure feline AGP.

methodsAGP was measured in sera and effusions from cats with FIP (n = 20) or with other diseases (n = 15). Precision was calculated based on the coefficient of variation (CV) of repeated testing, and accuracy was calculated by linearity under dilution (LUD).

resultsThe test is precise (intra-assay CVs: <6.0% in individual samples, <15.0% in pooled samples; inter-assay CVs <11.0% and <15.0%) and accurate (serum LUD r

conclusionThis ELISA method is precise and accurate. AGP in serum and in effusions is a useful diagnostic marker for FIP.

Indexed as

Enzyme-Linked Immunosorbent AssayFeline Infectious PeritonitisOrosomucoidAnimalsBiomarkersCatsFemaleMaleReproducibility of ResultsROC CurveSensitivity and SpecificityBiomarkersOrosomucoidaccuracyacute-phase proteinsAGPFIPlikelihood ratiosensitivityspecificityvalidation

Identifiers

PMID38668244
PMCPMC11055121
OpenAlexW4393930780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.