Evidence map›Paper›PMID 38668070›Full record

ReviewCurrent oncology (Toronto, Ont.)2024

Multimodal Approaches to Patient Selection for Pancreas Cancer Surgery.

Hala Muaddi, LaDonna Kearse, Susanne Warner

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hala MuaddiDivision of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN 55902, USA.ORCID 0000-0001-9721-2808
LaDonna KearseDivision of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN 55902, USA.
Susanne WarnerDivision of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN 55902, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With an overall 5-year survival rate of 12%, pancreas ductal adenocarcinoma (PDAC) is an aggressive cancer that claims more than 50,000 patient lives each year in the United States alone. Even those few patients who undergo curative-intent resection with favorable pathology reports are likely to experience recurrence within the first two years after surgery and ultimately die from their cancer. We hypothesize that risk factors for these early recurrences can be identified with thorough preoperative staging, thus enabling proper patient selection for surgical resection and avoiding unnecessary harm. Herein, we review evidence supporting multidisciplinary and multimodality staging, comprehensive neoadjuvant treatment strategies, and optimal patient selection for curative-intent surgical resections. We further review data generated from our standardized approach at the Mayo Clinic and extrapolate to inform potential future investigations.

Indexed as

Pancreatic NeoplasmsPatient SelectionCarcinoma, Pancreatic DuctalCombined Modality TherapyHumansNeoplasm Stagingneoadjuvant treatmentpancreatic ductal adenocarcinoma

Identifiers

PMID38668070
PMCPMC11049254

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.