Evidence map›Paper›PMID 38668035›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Prognosis versus Actual Outcomes in Stereotactic Radiosurgery of Brain Metastases: Reliability of Common Prognostic Parameters and Indices.

Julian Mangesius, Thomas Seppi, Christoph Reinhold Arnold, Stephanie Mangesius, Johannes Kerschbaumer, Matthias Demetz, Danijela Minasch, Samuel Moritz Vorbach, Manuel Sarcletti, Peter Lukas and 2 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Julian MangesiusDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-0855-1870
Thomas SeppiDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christoph Reinhold ArnoldDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-8813-342X
Stephanie MangesiusDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5790-2724
Johannes KerschbaumerDepartment of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Matthias DemetzDepartment of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Danijela MinaschDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Samuel Moritz VorbachDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0009-0003-1711-1604
Manuel SarclettiDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Peter LukasDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Meinhard Nevinny-StickelDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Ute GanswindtDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Innsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to evaluate the clinical outcome of stereotactic radiosurgery as the sole treatment for brain metastases and to assess prognostic factors influencing survival. A total of 108 consecutive patients with 213 metastases were retrospectively analyzed. Treatment was determined with close-meshed MRI follow-up. Various prognostic factors were assessed, and several prognostic indices were compared regarding their reliability to estimate overall survival. Median overall survival was 15 months; one-year overall survival was 50.5%. Both one- and two-year local controls were 90.9%. The rate of new metastases after SRS was 49.1%. Multivariate analysis of prognostic factors revealed that the presence of extracranial metastases, male sex, lower KPI, and progressive extracranial disease were significant risk factors for decreased survival. Of all evaluated prognostic indices, the Basic Score for Brain Metastases (BSBMs) showed the best correlation with overall survival. A substantial survival advantage was found for female patients after SRS when compared to male patients (18 versus 9 months,

Indexed as

Brain NeoplasmsRadiosurgeryAdultAgedAged, 80 and overFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisTreatment OutcomeYoung Adultbrain metastasesoutcomeprognosisprognostic scoresradiosurgerysex differences

Identifiers

PMID38668035
PMCPMC11049204
OpenAlexW4393187485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.