Evidence map›Paper›PMID 38667777›Full record

ArticleMarine drugs2024

Porous Nano-Fiber Structure of Modified Electrospun Chitosan GBR Membranes Improve Osteoblast Calcium Phosphate Deposition in Osteoblast-Fibroblast Co-Cultures.

Hengjie Su, Tomoko Fujiwara, Omar Skalli, Gretchen Schreyack Selders, Ting Li, Linna Mao, Joel D Bumgardner

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hengjie SuInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.ORCID 0009-0007-8176-9549
Tomoko FujiwaraDepartment of Chemistry, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-3329-0361
Omar SkalliIntegrated Microscopy Center, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0001-9356-3918
Gretchen Schreyack SeldersDepartment of Biomedical Engineering, University of Tennessee Health Science Center-Memphis Joint Graduate Biomedical Engineering Program, The University of Memphis, Memphis, TN 38152, USA.
Ting LiInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.ORCID 0000-0001-5145-3024
Linna MaoInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Joel D BumgardnerDepartment of Biomedical Engineering, University of Tennessee Health Science Center-Memphis Joint Graduate Biomedical Engineering Program, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-7467-3078
University of Tennessee Health Science Center · USChinese Academy of Medical Sciences & Peking Union Medical College · CNUniversity of Memphis · US

Funding

CAMS Innovation Fund for Medical Sciences 2022-I2M-C&T-B-012Chinese Academy of Medical Science health innovation project 2021-I2M-1-042Chinese Academy of Medical Science health innovation project 2021-I2M-1-058Chinese Academy of Medical Science health innovation project 2022-I2M-C&T-A-005Fundamental Research Funds for the Central Universities 3332023070Tianjin Outstanding Youth Fund Project 20JCJQIC00230
6 · The paper itself

Abstract

Desirable characteristics of electrospun chitosan membranes (ESCM) for guided bone regeneration are their nanofiber structure that mimics the extracellular fiber matrix and porosity for the exchange of signals between bone and soft tissue compartments. However, ESCM are susceptible to swelling and loss of nanofiber and porous structure in physiological environments. A novel post-electrospinning method using di-tert-butyl dicarbonate (tBOC) prevents swelling and loss of nanofibrous structure better than sodium carbonate treatments. This study aimed to evaluate the hypothesis that retention of nanofiber morphology and high porosity of tBOC-modified ESCM (tBOC-ESCM) would support more bone mineralization in osteoblast-fibroblast co-cultures compared to Na

Indexed as

Calcium PhosphatesChitosanCoculture TechniquesFibroblastsNanofibersOsteoblastsAnimalsBone RegenerationCalcification, PhysiologicCarbonatesMicePorosityTissue Scaffoldscalcium phosphateCalcium PhosphatesCarbonatesChitosancalcium phosphate depositionchitosanco-cultureelectrospinningguided bone regeneration

Identifiers

PMID38667777
PMCPMC11051071
OpenAlexW4393353100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.